Drug Interactions between Zoloft and Topamax
This report displays the potential drug interactions for the following 2 drugs:
- Zoloft (sertraline)
- Topamax (topiramate)
Interactions between your drugs
Applies to: Zoloft (sertraline) and Topamax (topiramate)
Treatment with sertraline may occasionally cause blood sodium levels to get too low, a condition known as hyponatremia, and using it with topiramate can increase that risk. In addition, sertraline can cause seizures in susceptible patients, which may reduce the effectiveness of medications that are used to control seizures such as topiramate. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek medical attention if you experience nausea, vomiting, headache, lethargy, irritability, difficulty concentrating, memory impairment, confusion, muscle spasm, weakness or unsteadiness, as these may be symptoms of hyponatremia. More severe cases may lead to hallucination, fainting, seizure, coma, and even death. Also let your doctor know if you develop seizures or experience an increase in seizures during treatment with sertraline. Additionally, because these medications may cause dizziness, drowsiness, and impairment in judgment, reaction speed and motor coordination, you should avoid driving or operating hazardous machinery until you know how they affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: Zoloft (sertraline)
You should avoid or limit the use of alcohol while being treated with sertraline. Alcohol can increase the nervous system side effects of sertraline such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Drug Interaction Classification
|No interaction information available.|