Samsca Interactions
There are 350 drugs known to interact with Samsca (tolvaptan), along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 75 are major, 267 are moderate, and 8 are minor.
- View all 350 medications that may interact with Samsca
- View Samsca alcohol/food interactions (1)
- View Samsca disease interactions (3)
Most frequently checked interactions
View interaction reports for Samsca (tolvaptan) and the medicines listed below.
- acetaminophen / oxycodone
- Actemra (tocilizumab)
- Advair Diskus (fluticasone / salmeterol)
- Advate (antihemophilic factor)
- albuterol
- Aldactone (spironolactone)
- allopurinol
- amiodarone
- amlodipine
- amlodipine / benazepril
- atorvastatin
- Bactrim (sulfamethoxazole / trimethoprim)
- buspirone
- demeclocycline
- Eliquis (apixaban)
- Lasix (furosemide)
- levetiracetam
- levothyroxine
- methotrexate
- metoprolol
- midodrine
- Nexium (esomeprazole)
- omeprazole
- pantoprazole
- Remicade (infliximab)
- ropinirole
- spironolactone
- tacrolimus
- trazodone
- ure-Na (urea)
Samsca alcohol/food interactions
There is 1 alcohol/food interaction with Samsca (tolvaptan).
Samsca disease interactions
There are 3 disease interactions with Samsca (tolvaptan) which include:
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More about Samsca (tolvaptan)
- Samsca consumer information
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- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: vasopressin antagonists
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
