Samsca Interactions
There are 352 drugs known to interact with Samsca (tolvaptan), along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 75 are major, 268 are moderate, and 9 are minor.
- View all 352 medications that may interact with Samsca
- View Samsca alcohol/food interactions (1)
- View Samsca disease interactions (3)
Most frequently checked interactions
View interaction reports for Samsca (tolvaptan) and the medicines listed below.
- acetaminophen / oxycodone
- Actemra (tocilizumab)
- Advair Diskus (fluticasone / salmeterol)
- Advate (antihemophilic factor)
- albuterol
- Aldactone (spironolactone)
- allopurinol
- amiodarone
- amlodipine
- amlodipine / benazepril
- atorvastatin
- Bactrim (sulfamethoxazole / trimethoprim)
- buspirone
- demeclocycline
- Eliquis (apixaban)
- Lasix (furosemide)
- levetiracetam
- levothyroxine
- methotrexate
- metoprolol
- midodrine
- Nexium (esomeprazole)
- omeprazole
- pantoprazole
- Remicade (infliximab)
- ropinirole
- spironolactone
- tacrolimus
- trazodone
- ure-Na (urea)
Samsca alcohol/food interactions
There is 1 alcohol/food interaction with Samsca (tolvaptan).
Samsca disease interactions
There are 3 disease interactions with Samsca (tolvaptan) which include:
Report options
More about Samsca (tolvaptan)
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- Side effects
- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: vasopressin antagonists
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Ozempic
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Vaprisol
Vaprisol (conivaptan) is used to treat hyponatremia (low levels of sodium in the blood). Includes ...
Conivaptan
Conivaptan systemic is used for euvolemic hyponatremia, SIADH
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
