Sirolimus Drug Interactions
Currently displaying a list of 718 drugs known to interact with sirolimus.
- 182 major drug interactions
- 525 moderate drug interactions
- 11 minor drug interactions
Medications known to interact with sirolimus
Note: Showing generic names only.
A
- abametapir topical
- abrocitinib
- acarbose
- acetohexamide
- acyclovir
- adagrasib
- adalimumab
- adefovir
- adenovirus vaccine
- albendazole
- albiglutide
- alefacept
- alemtuzumab
- alfentanil
- aliskiren
- allogeneic processed thymus tissue
- almotriptan
- alogliptin
- alpelisib
- alprazolam
- amikacin
- amikacin liposome
- aminoglutethimide
- amiodarone
- amlodipine
- amobarbital
- amphotericin b
- amphotericin b cholesteryl sulfate
- amphotericin b lipid complex
- amphotericin b liposomal
- amprenavir
- anakinra
- anthrax vaccine adsorbed
- apalutamide
- aprepitant
- aripiprazole
- armodafinil
- asciminib
- ashwaganda
- astemizole
- atazanavir
- atezolizumab
- atorvastatin
- avacopan
- avelumab
- azathioprine
- azilsartan medoxomil
B
- bacitracin
- balsalazide
- baricitinib
- bcg
- bcg vaccine
- belzutifan
- benazepril
- benzgalantamine
- benzphetamine
- bepridil
- berotralstat
- betamethasone
- bexagliflozin
- bexarotene
- bicalutamide
- bifidobacterium infantis
- bifidobacterium longum
- bimekizumab
- blinatumomab
- boceprevir
- bosentan
- botulism immune globulin
- brewer's yeast
- brexpiprazole
- brigatinib
- brodalumab
- bromfenac
- bromocriptine
- budesonide
- buprenorphine
- buspirone
- busulfan
- butabarbital
- butalbital
C
- cabazitaxel
- cabozantinib
- canagliflozin
- canakinumab
- candesartan
- candida albicans extract
- cannabidiol
- cannabis
- capivasertib
- capmatinib
- capreomycin
- captopril
- carbamazepine
- cat's claw
- celecoxib
- cemiplimab
- cenobamate
- ceritinib
- cerivastatin
- certolizumab
- cevimeline
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chlordiazepoxide
- chlorotrianisene
- chlorpropamide
- cholera vaccine
- cholera vaccine, live
- cholestyramine
- cidofovir
- cilostazol
- cimetidine
- cisapride
- cisplatin
- citalopram
- cladribine
- clarithromycin
- clobazam
- clofarabine
- clofazimine
- clofibrate
- clonazepam
- clorazepate
- clotrimazole
- cobicistat
- cocaine nasal
- cocaine topical
- coccidioidin skin test
- colchicine
- colesevelam
- colestipol
- colistimethate
- conivaptan
- cortisone
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclobenzaprine
- cyclophosphamide
- cyclosporine
- cytomegalovirus immune globulin
D
- dabrafenib
- daclatasvir
- danazol
- danicopan
- dapagliflozin
- dapsone
- daridorexant
- darunavir
- dasatinib
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delavirdine
- dengue vaccine
- denosumab
- deucravacitinib
- dexamethasone
- dextrothyroxine sodium
- diatrizoate
- diazepam
- diclofenac
- diflunisal
- digitoxin
- dihydroergotamine
- diltiazem
- dimethyl fumarate
- diroximel fumarate
- disopyramide
- docetaxel
- dofetilide
- doravirine
- dostarlimab
- doxorubicin
- doxorubicin liposomal
- dronabinol
- dronedarone
- dulaglutide
- durvalumab
- dutasteride
- duvelisib
E
- echinacea
- efalizumab
- efavirenz
- elacestrant
- elafibranor
- elagolix
- elderberry
- eletriptan
- eliglustat
- elranatamab
- eluxadoline
- emapalumab
- empagliflozin
- enalapril
- enalaprilat
- encorafenib
- entecavir
- entrectinib
- enzalutamide
- epcoritamab
- eplerenone
- eprosartan
- erdafitinib
- ergonovine
- ergotamine
- ertugliflozin
- erythromycin
- estazolam
- estradiol
- estradiol topical
- estrone
- etanercept
- ethinyl estradiol
- ethosuximide
- etidronate
- etodolac
- etonogestrel
- etoposide
- etrasimod
- etravirine
- exemestane
- exenatide
- ezetimibe
F
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenofibrate
- fenoprofen
- fentanyl
- fexinidazole
- fidaxomicin
- finasteride
- fingolimod
- flibanserin
- fluconazole
- flucytosine
- fludrocortisone
- flurazepam
- flurbiprofen
- fluvastatin
- fluvoxamine
- fosamprenavir
- fosaprepitant
- foscarnet
- fosinopril
- fosphenytoin
- fostamatinib
- futibatinib
G
- galantamine
- gallium nitrate
- gemfibrozil
- gentamicin
- gepirone
- gilteritinib
- givinostat
- givosiran
- glasdegib
- glimepiride
- glipizide
- glofitamab
- glyburide
- glycerol phenylbutyrate
- golimumab
- granisetron
- grepafloxacin
- griseofulvin
- guselkumab
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- halazepam
- halofantrine
- haloperidol
- halothane
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
- hydrocortisone
- hydroxychloroquine
- hydroxyprogesterone
I
- ibandronate
- ibrutinib
- ibuprofen
- idelalisib
- ifosfamide
- imatinib
- imipramine
- immune globulin intravenous
- immune globulin intravenous and subcutaneous
- indinavir
- indomethacin
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotersen
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iobenguane I 131
- iodamide
- iodipamide
- iodixanol
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- ipilimumab
- iptacopan
- irbesartan
- irinotecan
- isavuconazonium
- isradipine
- istradefylline
- itraconazole
- ivacaftor
- ivermectin
- ivosidenib
- ixekizumab
J
K
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lansoprazole
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lenacapavir
- lesinurad
- letermovir
- letrozole
- levacetylleucine
- levamlodipine
- levobupivacaine
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- lidocaine
- lifileucel
- linagliptin
- liraglutide
- lisinopril
- lithium
- lixisenatide
- lomitapide
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- loratadine
- lorlatinib
- losartan
- lovastatin
- lumateperone
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lyme disease vaccine
M
- maribavir
- mavacamten
- mavorixafor
- measles virus vaccine
- meclofenamate
- medroxyprogesterone
- mefenamic acid
- mefloquine
- meloxicam
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephobarbital
- mesalamine
- metformin
- methadone
- methotrexate
- methoxyflurane
- methylergonovine
- methylprednisolone
- metoclopramide
- metreleptin
- metrizamide
- mibefradil
- micafungin
- miconazole
- midazolam
- midostaurin
- mifepristone
- miglitol
- mirabegron
- mirikizumab
- mirtazapine
- mitapivat
- mitotane
- mixed respiratory vaccine
- mobocertinib
- modafinil
- moexipril
- monomethyl fumarate
- mosunetuzumab
- moxetumomab pasudotox
- mumps skin test antigen
- mumps virus vaccine
- mycophenolate mofetil
- mycophenolic acid
N
- nabumetone
- nadofaragene firadenovec
- nafcillin
- naproxen
- natalizumab
- nateglinide
- nefazodone
- nelfinavir
- nemolizumab
- neomycin
- neratinib
- netilmicin
- nevirapine
- niacin
- nicardipine
- nicotinamide
- nifedipine
- nilotinib
- nimodipine
- niraparib
- nirogacestat
- nisoldipine
- nivolumab
- norethindrone
- norgestrel
O
- ocrelizumab
- olaparib
- oliceridine
- olmesartan
- olsalazine
- olutasidenib
- omacetaxine
- omaveloxolone
- oritavancin
- osilodrostat
- osimertinib
- oxaliplatin
- oxaprozin
- oxcarbazepine
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- pamidronate
- pazopanib
- pembrolizumab
- pemetrexed
- pemigatinib
- pentamidine
- pentobarbital
- perindopril
- pertussis, acellular
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pimecrolimus topical
- pimozide
- pioglitazone
- piroxicam
- pirtobrutinib
- pitavastatin
- plague vaccine
- plazomicin
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- polymyxin b
- ponatinib
- ponesimod
- posaconazole
- pralsetinib
- pramlintide
- pravastatin
- prednisone
- pretomanid
- primidone
- probucol
- progesterone
- progesterone topical
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- ramipril
- ranolazine
- red yeast rice
- remdesivir
- repaglinide
- repotrectinib
- respiratory syncytial virus immune globulin
- retifanlimab
- rho (d) immune globulin
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- ripretinib
- risankizumab
- ritlecitinib
- ritonavir
- rofecoxib
- roflumilast
- rolapitant
- ropeginterferon alfa-2b
- rosiglitazone
- rosuvastatin
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
- ruxolitinib topical
S
- saccharomyces boulardii lyo
- salsalate
- saquinavir
- sarecycline
- sarilumab
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- satralizumab
- saxagliptin
- secobarbital
- secukinumab
- selpercatinib
- semaglutide
- sertraline
- sibutramine
- sildenafil
- siltuximab
- simeprevir
- simvastatin
- siponimod
- sipuleucel-T
- sitagliptin
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotagliflozin
- sotorasib
- st. john's wort
- staphage lysate (spl)
- stiripentol
- streptococcus salivarius
- streptomycin
- sufentanil
- sulfasalazine
- sulfinpyrazone
- sulindac
- suzetrigine
T
- talimogene laherparepvec
- talquetamab
- tamoxifen
- tarlatamab
- tazemetostat
- tebentafusp
- teclistamab
- tecovirimat
- telaprevir
- telavancin
- telbivudine
- telithromycin
- telmisartan
- telotristat
- temsirolimus
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- terfenadine
- teriflunomide
- testosterone
- testosterone topical
- tetanus toxoid
- theophylline
- tiagabine
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tildrakizumab
- tipranavir
- tirzepatide
- tislelizumab
- tobramycin
- tocilizumab
- tofacitinib
- tolazamide
- tolbutamide
- tolmetin
- tolterodine
- tolvaptan
- toremifene
- toripalimab
- tovorafenib
- trandolapril
- trazodone
- tremelimumab
- treosulfan
- triamcinolone
- triazolam
- trichophyton skin test
- trofinetide
- troglitazone
- troleandomycin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valacyclovir
- valdecoxib
- valsartan
- vancomycin
- varicella virus vaccine
- vemurafenib
- venetoclax
- verapamil
- vibegron
- viloxazine
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vitamin e
- voclosporin
- vonoprazan
- vorasidenib
- voriconazole
- voxelotor
Y
Z
- zaleplon
- zidovudine
- zileuton
- zinc acetate
- zinc chloride
- zinc gluconate
- zinc sulfate
- ziprasidone
- zoledronic acid
- zolpidem
- zonisamide
- zoster vaccine live
- zoster vaccine, recombinant
Sirolimus alcohol/food interactions
There are 2 alcohol/food interactions with sirolimus.
Sirolimus disease interactions
There are 9 disease interactions with sirolimus which include:
- infections
- PML
- angioedema
- hyperlipidemia
- liver disease
- liver transplantation
- lung dysfunction
- lung transplant
- renal dysfunction
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More about sirolimus
- sirolimus consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (8)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: mTOR inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
