Drug Interactions between ranolazine and Vitamin B12
This report displays the potential drug interactions for the following 2 drugs:
- ranolazine
- Vitamin B12 (cyanocobalamin)
Interactions between your drugs
No interactions were found between ranolazine and Vitamin B12. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
ranolazine
A total of 525 drugs are known to interact with ranolazine.
- Ranolazine is in the drug class antianginal agents.
- Ranolazine is used to treat Angina.
Vitamin B12
A total of 15 drugs are known to interact with Vitamin B12.
- Vitamin b12 is in the drug class vitamins.
- Vitamin b12 is used to treat the following conditions:
Drug and food interactions
ranolazine food
Applies to: ranolazine
GENERALLY AVOID: Grapefruit and grapefruit juice may significantly increase the plasma concentrations of orally administered ranolazine. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruit. Because ranolazine prolongs QT interval in a dose-dependent manner, high plasma levels of ranolazine may increase the risk of ventricular arrhythmias such as ventricular tachycardia, ventricular fibrillation, and torsade de pointes.
MANAGEMENT: Patients treated with ranolazine should avoid consumption of grapefruit juice and other grapefruit products if possible. Otherwise, the dosage of ranolazine should be limited to 500 mg twice a day.
References
- (2006) "Product Information. Ranexa (ranolazine)." Calmoseptine Inc
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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