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Drug Interactions between Provera and rosuvastatin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Minor

medroxyPROGESTERone rosuvastatin

Applies to: Provera (medroxyprogesterone) and rosuvastatin

Coadministration with rosuvastatin may increase the plasma concentrations of certain oral contraceptive hormones. The mechanism of interaction has not been established. According to the manufacturer, concomitant use of rosuvastatin and an oral contraceptive resulted in an increase in ethinyl estradiol and norgestrel area under the plasma concentration-time curve (AUC) of 26% and 34%, respectively. The clinical significance of these alterations is unknown but should be considered when selecting oral contraceptive doses.

References (1)
  1. (2003) "Product Information. Crestor (rosuvastatin)." AstraZeneca Pharma Inc

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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