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Drug interactions between penicillamine and trientine

Results for the following 2 drugs:
penicillamine
trientine

Interactions between your drugs

There were no interactions found in our database between penicillamine and trientine - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

penicillamine

A total of 167 drugs (1867 brand and generic names) are known to interact with penicillamine.

trientine

A total of 98 drugs (1620 brand and generic names) are known to interact with trientine.

Drug and food interactions

Moderate

penicillAMINE food

Applies to: penicillamine

You may experience reduced absorption of penicillAMINE in the presence of food. The effectiveness of the antibiotic may be reduced. PenicillAMINE should be administered one hour before or two hours after meals and at least one hour apart from any other drug, food, or milk. This will make it easier for your body to absorb the medication.

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Moderate

trientine food

Applies to: trientine

Take trientine on an empty stomach 1 hour before or 2 hours after a meal and at least one hour apart from any other food, drug, or milk. You may experience reduced absorption of trientine in the presence of food or milk. The capsules should be swallowed whole with water and should not be opened or chewed.

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Copper chelating agents

Therapeutic duplication

The recommended maximum number of medicines in the 'copper chelating agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'copper chelating agents' category:

  • penicillamine
  • trientine

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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