Skip to main content

Can you take Nexa Plus with DHA with Vonoprazan?

1 drug interaction and 5 additional warnings found for the following 2 drugs:

Add/remove drugs

Drug interactions

Moderate drug interactions

Moderate:

multivitamins, prenatal vonoprazan

Applies to: Nexa Plus with DHA (multivitamin, prenatal) and vonoprazan

If you are iron-deficient or have anemia, you should talk to your doctor before using multivitamins, prenatal together with vonoprazan. By reducing stomach acid, vonoprazan may reduce the absorption of iron and make multivitamins, prenatal less effective in treating your condition. Your doctor or pharmacist may be able to offer suggestions on safer alternatives if you require treatment for stomach acid or ulcer while you are being treated with multivitamins, prenatal. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food/lifestyle interactions

Moderate food/lifestyle interactions

Moderate:

multivitamins, prenatal Food/Lifestyle

Applies to: Nexa Plus with DHA (multivitamin, prenatal)

Food may reduce the absorption and blood levels of multivitamins, prenatal. In addition, some oral medications can also interfere with multivitamins, prenatal absorption into the bloodstream, which may make the medication less effective in treating your condition. Likewise, multivitamins, prenatal may interfere with the absorption of other orally administered medications. You should take multivitamins, prenatal on an empty stomach at least one hour before or two hours after a meal. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Talk to your doctor or pharmacist if you have questions about how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Disease interactions

4 potential interactions Applies to: 4 conditions, including Osteoporosis, Hypokalemia, Hypocalcemia, and Magnesium Imbalance.

Hypocalcemia

Moderate:

vonoprazan

Vonoprazan has a moderate potential interaction with Hypocalcemia.

Postmarketing cases of hypomagnesemia have been reported with vonoprazan. Hypomagnesemia may lead to hypocalcemia and/or hypokalemia and may exacerbate underlying hypocalcemia in at-risk patients. Monitor magnesium and calcium levels regularly in patients with a preexisting risk of hypocalcemia (e.g., hypoparathyroidism). Monitor magnesium levels prior to initiating therapy with vonoprazan in all patients, and then periodically while on treatment. Monitor magnesium levels closely in patients taking drugs that may have increased toxicity in the presence of hypomagnesemia (e.g., digoxin), or drugs that may cause hypomagnesemia (e.g., diuretics).

Hypokalemia

Moderate:

vonoprazan

Vonoprazan has a moderate potential interaction with Hypokalemia.

Postmarketing cases of hypomagnesemia have been reported with vonoprazan. Hypomagnesemia may lead to hypocalcemia and/or hypokalemia and may exacerbate underlying hypocalcemia in at-risk patients. Monitor magnesium and calcium levels regularly in patients with a preexisting risk of hypocalcemia (e.g., hypoparathyroidism). Monitor magnesium levels prior to initiating therapy with vonoprazan in all patients, and then periodically while on treatment. Monitor magnesium levels closely in patients taking drugs that may have increased toxicity in the presence of hypomagnesemia (e.g., digoxin), or drugs that may cause hypomagnesemia (e.g., diuretics).

Magnesium Imbalance

Moderate:

vonoprazan

Vonoprazan has a moderate potential interaction with Magnesium Imbalance.

Postmarketing cases of hypomagnesemia have been reported with vonoprazan. Hypomagnesemia may lead to hypocalcemia and/or hypokalemia and may exacerbate underlying hypocalcemia in at-risk patients. Monitor magnesium and calcium levels regularly in patients with a preexisting risk of hypocalcemia (e.g., hypoparathyroidism). Monitor magnesium levels prior to initiating therapy with vonoprazan in all patients, and then periodically while on treatment. Monitor magnesium levels closely in patients taking drugs that may have increased toxicity in the presence of hypomagnesemia (e.g., digoxin), or drugs that may cause hypomagnesemia (e.g., diuretics).

Osteoporosis

Moderate:

vonoprazan

Vonoprazan has a moderate potential interaction with Osteoporosis.

Various published observational studies have reported that PPI therapy may be associated with an increased risk for osteoporosis related fractures of the hip, wrist or spine. The risk was increased in patients who received high doses (multiple daily doses), and long term treatment (a year or longer). Patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated. Caution should be used in patients at risk for osteoporosis related fractures and should be managed according to established treatment guidelines.

More resources

Nexa Plus with DHA

A total of 172 drugs are known to interact with Nexa Plus with DHA.

vonoprazan

A total of 404 drugs are known to interact with vonoprazan.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.