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Drug Interactions between Mudrane and Premphase

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

medroxyPROGESTERone PHENobarbital

Applies to: Premphase (conjugated estrogens / medroxyprogesterone) and Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide)

PHENobarbital may decrease the blood levels and effects of medroxyPROGESTERone. You may need a dose adjustment if you have been taking medroxyPROGESTERone and are starting treatment with PHENobarbital. Contact your doctor if your condition changes during treatment with these medications. The interaction is not expected to occur if you are getting medroxyPROGESTERone by shot for birth control. However, let your doctor know if you experience bleeding outside of your menstrual cycle, since it may indicate reduced effectiveness of medroxyPROGESTERone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

PHENobarbital conjugated estrogens

Applies to: Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide) and Premphase (conjugated estrogens / medroxyprogesterone)

PHENobarbital may reduce the blood levels and effects of conjugated estrogens. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

PHENobarbital aminophylline

Applies to: Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide) and Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide)

Using PHENobarbital together with aminophylline may decrease the effects of aminophylline. Contact your doctor if your condition changes or if you experience breathing difficulties. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

ePHEDrine aminophylline

Applies to: Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide) and Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Major

PHENobarbital food

Applies to: Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide)

Ask your doctor before using PHENobarbital together with ethanol, this can add to dizziness, drowsiness and other side effects of PHENobarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with PHENobarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

ePHEDrine food

Applies to: Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide)

Both ePHEDrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aminophylline food

Applies to: Mudrane (aminophylline / ephedrine / phenobarbital / potassium iodide)

Both aminophylline and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

conjugated estrogens food

Applies to: Premphase (conjugated estrogens / medroxyprogesterone)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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