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Drug Interactions between MTE-6 and sodium iodide-i-131

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

sodium iodide I-131 sodium iodide

Applies to: sodium iodide-i-131 and MTE-6 (trace elements with selenium and iodide)

ADJUST DOSING INTERVAL: Iodine-containing products may affect the pharmacokinetics, pharmacodynamics, and/or diagnostic results of radioiodides. These effects may last up to 8 weeks.

MANAGEMENT: Iodine preparations including expectorants, vitamins, topicals, and intravascular iodine-containing contrast media should be withheld for at least 2 to 4 weeks and possibly longer, and cholecystographic agents should be withheld for more than 4 weeks, prior to administration of sodium iodide I-131 or I-123.

References

  1. (2001) "Product Information. Visipaque (iodixanol)." Nycomed Inc
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics."
  3. (2022) "Product Information. Sodium Iodide I-123 (sodium iodide I-123)." GE Healthcare
  4. Cerner Multum, Inc. "Australian Product Information."
View all 4 references

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Drug and food interactions

Moderate

sodium iodide I-131 food

Applies to: sodium iodide-i-131

MONITOR: Excessive intake of dietary iodine (e.g., iodised salt) may interfere with adequate uptake of radioiodide by the thyroid .

MANAGEMENT: A diet low in iodine is recommended before initiating therapy with sodium iodide I-131 or I-123.

References

  1. Cerner Multum, Inc. "Australian Product Information."

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Moderate

sodium iodide I-131 food

Applies to: sodium iodide-i-131

ADJUST DOSING INTERVAL: Certain drugs may affect the pharmacokinetics, pharmacodynamics, and/or diagnostic results of radioiodides.

MANAGEMENT: Antithyroid agents such as carbimazole or propylthiouracil should generally be withheld for 1 week before administration of sodium iodide I-131 or I-123, and for a few days afterward. Salicylates, steroids, anticoagulants, antihistamines, antiparasitics, penicillins, sulfonamides, tolbutamide, thiopental, and nitroprusside should generally be withheld for 1 week. Amiodarone, lithium, and benzodiazepines should be withheld for at least 4 weeks.

References

  1. (2022) "Product Information. Sodium Iodide I-123 (sodium iodide I-123)." GE Healthcare

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.