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Drug Interactions between modafinil and NuvaRing

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

ethinyl estradiol modafinil

Applies to: NuvaRing (ethinyl estradiol / etonogestrel) and modafinil

Using ethinyl estradiol together with modafinil may decrease the effectiveness of ethinyl estradiol. If you are using low-dose oral contraceptives you may have an increased risk of breakthrough bleeding and unintended pregnancy. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take hormone replacement for menopause, notify your doctor if you have decreased efficacy of your hormones such as increased hot flashes, vaginal dryness or menstrual problems. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Moderate

modafinil etonogestrel

Applies to: modafinil and NuvaRing (ethinyl estradiol / etonogestrel)

Using etonogestrel together with modafinil may decrease the effectiveness of etonogestrel. If you are using low-dose oral contraceptives you may have an increased risk of breakthrough bleeding and unintended pregnancy. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take hormone replacement for menopause, notify your doctor if you have decreased efficacy of your hormones such as increased hot flashes, vaginal dryness or menstrual problems. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Drug and food interactions

Moderate

etonogestrel food

Applies to: NuvaRing (ethinyl estradiol / etonogestrel)

Grapefruit juice may increase the blood levels of certain medications such as etonogestrel. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with etonogestrel. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Minor

ethinyl estradiol food

Applies to: NuvaRing (ethinyl estradiol / etonogestrel)

Information for this minor interaction is available on the professional version.

Minor

modafinil food

Applies to: modafinil

Information for this minor interaction is available on the professional version.

Minor

ethinyl estradiol food

Applies to: NuvaRing (ethinyl estradiol / etonogestrel)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer