Drug Interactions between methylphenidate and midodrine
This report displays the potential drug interactions for the following 2 drugs:
- methylphenidate
- midodrine
Interactions between your drugs
methylphenidate midodrine
Applies to: methylphenidate and midodrine
Using midodrine together with methylphenidate can increase the risk of hypertension. Midodrine may cause significant increases in blood pressure by constricting the blood vessels, and the risk for complications may be increased when used with other drugs that also affect blood pressure such as decongestants, stimulants, and certain medications for headache, glaucoma, or eye redness relief. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor immediately if you experience symptoms that could indicate an acute increase in blood pressure, such as severe or throbbing headache, pounding in the ears, chest pain, and blurred vision. In some cases, sleeping with the head of the bed elevated or taking the last daily dose of midodrine 3 to 4 hours before bedtime may help lessen the effects on blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
methylphenidate food
Applies to: methylphenidate
Do not use alcohol or medications that contain alcohol while you are receiving treatment with methylphenidate. This may increase nervous system side effects such as drowsiness, anxiety, depression, and seizures. In addition, with certain long-acting forms of methylphenidate, alcohol can cause too much of the drug to be released at one time. High blood levels of the drug may increase the risk of side effects. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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