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Drug Interactions between Merzee and porfimer

This report displays the potential drug interactions for the following 2 drugs:

  • Merzee (ethinyl estradiol/norethindrone)
  • porfimer

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Interactions between your drugs


ethinyl estradiol porfimer

Applies to: Merzee (ethinyl estradiol / norethindrone) and porfimer

Using porfimer together with ethinyl estradiol may increase the risk of a photosensitivity reaction such as a severe sunburn. It is recommended that ethinyl estradiol be avoided for at least 30 days following therapy with porfimer, and until a test for residual photosensitivity shows no photosensitivity reaction (erythema, edema, blistering) within 24 hours. In some cases, it might be necessary to avoid photosensitizing medications for 90 days or longer, although it may not be feasible to interrupt some treatments for that long, especially if they are medically necessary. Check with your doctor to see if you should temporarily withhold any of your medications after taking porfimer. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions


norethindrone food

Applies to: Merzee (ethinyl estradiol / norethindrone)

Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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ethinyl estradiol food

Applies to: Merzee (ethinyl estradiol / norethindrone)

Information for this minor interaction is only available at a professional reading level.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.