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Drug Interactions between Lonsurf and tipiracil / trifluridine

This report displays the potential drug interactions for the following 2 drugs:

  • Lonsurf (tipiracil/trifluridine)
  • tipiracil/trifluridine

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Interactions between your drugs

No interactions were found between Lonsurf and tipiracil / trifluridine. This does not necessarily mean no interactions exist. Always consult your healthcare provider.


A total of 137 drugs are known to interact with Lonsurf.

tipiracil / trifluridine

A total of 137 drugs are known to interact with tipiracil / trifluridine.

Drug and food interactions


trifluridine food

Applies to: Lonsurf (tipiracil / trifluridine) and tipiracil / trifluridine

Trifluridine should be taken within one hour after eating your morning or evening meals. This may help to reduce the medication's harmful effects on white blood cells. Talk to you doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.