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Drug Interactions between lindane topical and methadone

This report displays the potential drug interactions for the following 2 drugs:

  • lindane topical
  • methadone

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Interactions between your drugs


methadone lindane topical

Applies to: methadone and lindane topical

Some of the medication in lindane topical can be absorbed through the skin into the bloodstream and produce seizures on rare occasions. The risk may be increased when used with other medications that can also cause seizures such as methadone. This may be more likely to occur in very young children or the elderly; people undergoing alcohol or drug withdrawal; and those who have a history of seizures or a condition affecting the central nervous system such as a brain tumor or head trauma. Excessive or inappropriate use or accidental ingestion of lindane topical can also lead to seizures. Talk to a healthcare professional if you have any questions or concerns. You should follow closely the instructions for use of lindane topical given by the prescriber, and keep the product out of reach of children. Do not exceed the frequency and duration of use recommended on the product label or prescribed by the doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions


methadone food

Applies to: methadone

Grapefruit juice can increase the blood levels and effects of methadone. If you regularly consume grapefruits or grapefruit juice, you should be monitored for side effects and/or changes in methadone levels. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Orange juice is not expected to interact.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.