Can you take Lactulose with Sulfolax?
1 drug interaction and 6 additional warnings found for the following 2 drugs:
- lactulose
- Sulfolax (docusate)
Drug interactions
Moderate drug interactions
Moderate:
docusate lactulose
Applies to: Sulfolax (docusate) and lactulose
If you are using lactulose for the treatment of a condition known as portal-systemic encephalopathy, you should talk to your doctor before using it with docusate.
Why: The loose stools produced by treatment with docusate may make it difficult to know when you have achieved an adequate dosage of lactulose.
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
6 potential interactions Applies to: 4 conditions, including Inflammatory Bowel Disease, Diabetes Mellitus, Galactosemia, and Gastrointestinal Obstruction.
Diabetes Mellitus
Moderate:
lactulose
Lactulose has a moderate potential interaction with Diabetes Mellitus.
Since lactulose solution contains galactose and lactose, it should be used cautiously in patients with diabetes.
Galactosemia
Major:
lactulose
Lactulose has a major potential interaction with Galactosemia.
Since lactulose solution contains galactose, use is contraindicated in patients who require a low galactose diet.
Gastrointestinal Obstruction
Major:
lactulose
Lactulose has a major potential interaction with Gastrointestinal Obstruction.
The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.
Major:
Sulfolax
The docusate in Sulfolax has a major potential interaction with Gastrointestinal Obstruction.
The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.
Inflammatory Bowel Disease
Major:
lactulose
Lactulose has a major potential interaction with Inflammatory Bowel Disease.
The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.
Major:
Sulfolax
The docusate in Sulfolax has a major potential interaction with Inflammatory Bowel Disease.
The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.
Report options
More resources
lactulose
A total of 274 drugs are known to interact with lactulose.
- Lactulose is in the drug class laxatives.
- Lactulose is used to treat the following conditions:
Sulfolax
A total of 203 drugs are known to interact with Sulfolax.
- Sulfolax is in the drug class laxatives.
- Sulfolax is used to treat Constipation.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.