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Drug Interactions between Keytruda and Tarceva

This report displays the potential drug interactions for the following 2 drugs:

  • Keytruda (pembrolizumab)
  • Tarceva (erlotinib)

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Interactions between your drugs

No interactions were found between Keytruda and Tarceva. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Keytruda

A total of 3 drugs are known to interact with Keytruda.

Tarceva

A total of 163 drugs are known to interact with Tarceva.

Drug and food interactions

Moderate

erlotinib food

Applies to: Tarceva (erlotinib)

Erlotinib should be taken on an empty stomach 1 hour before or 2 hours after a meal and at the same time each day unless otherwise directed by your doctor. You should also avoid grapefruit and grapefruit juice while taking erlotinib. Food and grapefruit can raise the levels of erlotinib in your body and lead to increased side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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