Can you take Halog with Insulin inhalation, rapid acting?
1 drug interaction and 22 additional warnings found for the following 2 drugs:
- Halog (halcinonide topical)
- insulin inhalation, rapid acting
Drug interactions
Moderate drug interactions
Moderate:
halcinonide topical insulin inhalation, rapid acting
Applies to: Halog (halcinonide topical) and insulin inhalation, rapid acting
Some of the medication in halcinonide topical may be absorbed into the bloodstream following application to your skin. When present in sufficient concentrations in the blood, steroids like halcinonide topical can interfere with blood sugar control and reduce the effectiveness of insulin inhalation, rapid acting and other diabetic medications. Although the absorption of most steroid preparations is limited when used as recommended in the product labeling, absorption may be increased under certain circumstances, such as: when the steroid is strong or highly potent; when the steroid is used for a longer duration; the person being treated is an infant or young child; or the area of skin being treated is large, inflamed, damaged (cut, scraped), thin (like the face), and/or covered with a dressing, wrapping or clothing. Blood sugar should be monitored closely in these situations. You may need a dose adjustment of insulin inhalation, rapid acting and/or other diabetic medications if your blood sugar is affected. Talk to your health care provider if you have any questions or concerns. Do not exceed the recommended dose or frequency and duration of use when treated with products that contain steroids, including some over-the counter products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
Moderate food/lifestyle interactions
Moderate:
insulin inhalation, rapid acting Food/Lifestyle
Applies to: insulin inhalation, rapid acting
Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Disease interactions
21 potential interactions Applies to: 19 conditions, including Asthma, COPD, Hypokalemia, Diabetes Mellitus, and Cataract.
Abnormal Glucose Tolerance
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Abnormal Glucose Tolerance.
Corticosteroids can raise blood glucose level by antagonizing the action and suppressing the secretion of insulin, which results in inhibition of peripheral glucose uptake and increased gluconeogenesis. Therapy with topical corticosteroids rarely produces these effects but should be administered cautiously nonetheless in patients with diabetes mellitus, glucose intolerance, or a predisposition to hyperglycemia. Systemic absorption of topical corticosteroids may occur depending on the vehicle and concentration of the preparation, the size of the application area, the integrity of the skin, and the duration of administration. Use of occlusive dressings over the applied areas may also increase percutaneous absorption. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios. If possible, the use of highly potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) should be avoided in children and limited to small areas for 2 weeks in adults.
Adrenal Insufficiency
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Adrenal Insufficiency.
Hypoglycemia may commonly occur during treatment with insulin and/or oral hypoglycemic agents. Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during the use of these drugs, including those who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents.
Anorexia/Feeding Problems
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Anorexia/Feeding Problems.
Hypoglycemia may commonly occur during treatment with insulin and/or oral hypoglycemic agents. Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during the use of these drugs, including those who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents.
Asthma
Major:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a major potential interaction with Asthma.
The use of inhaled insulin is contraindicated in patients with chronic lung disease such as asthma and COPD. Acute bronchospasm has been observed after an inhaled insulin dosage. Prior to initiating therapy with an inhaled insulin product, it is recommended to evaluate all patients medical history, physical examination and spirometry (FEV1) to identify potential underlying lung disease.
Autonomic Neuropathy
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Autonomic Neuropathy.
Hypoglycemia may commonly occur during treatment with insulin and/or oral hypoglycemic agents. Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during the use of these drugs, including those who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents.
Cataract
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Cataract.
Prolonged use of corticosteroids may cause posterior subcapsular cataracts and elevated intraocular pressure, the latter of which may lead to glaucoma and/or damage to the optic nerves. Therapy with topical corticosteroids rarely produces these effects but should be administered cautiously nonetheless in patients with a history of cataracts, glaucoma, or increased intraocular pressure, especially when potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) are used in the periorbital area. Topical corticosteroids may be systemically absorbed, depending on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios.
COPD
Major:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a major potential interaction with COPD.
The use of inhaled insulin is contraindicated in patients with chronic lung disease such as asthma and COPD. Acute bronchospasm has been observed after an inhaled insulin dosage. Prior to initiating therapy with an inhaled insulin product, it is recommended to evaluate all patients medical history, physical examination and spirometry (FEV1) to identify potential underlying lung disease.
Diabetes Mellitus
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Diabetes Mellitus.
Corticosteroids can raise blood glucose level by antagonizing the action and suppressing the secretion of insulin, which results in inhibition of peripheral glucose uptake and increased gluconeogenesis. Therapy with topical corticosteroids rarely produces these effects but should be administered cautiously nonetheless in patients with diabetes mellitus, glucose intolerance, or a predisposition to hyperglycemia. Systemic absorption of topical corticosteroids may occur depending on the vehicle and concentration of the preparation, the size of the application area, the integrity of the skin, and the duration of administration. Use of occlusive dressings over the applied areas may also increase percutaneous absorption. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios. If possible, the use of highly potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) should be avoided in children and limited to small areas for 2 weeks in adults.
Diaper Rash
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Diaper Rash.
Topical corticosteroids, especially the potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol), are generally not recommended for use in the treatment of diaper rash. Topical corticosteroids may be systemically absorbed, depending on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Given equivalent doses, small children are usually at the greatest risk for systemic toxicity such as adrenal suppression, Cushing's syndrome and intracranial hypertension because of their larger skin surface to body mass ratios. If topical corticosteroids are necessary to treat diaper rash, medium- to low-potency agents should preferably be used, and parents should be advised not to put tight-fitting diapers or plastic pants over the rash, since occlusion of treated area may increase percutaneous drug absorption.
Glaucoma/Intraocular Hypertension
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Glaucoma/Intraocular Hypertension.
Prolonged use of corticosteroids may cause posterior subcapsular cataracts and elevated intraocular pressure, the latter of which may lead to glaucoma and/or damage to the optic nerves. Therapy with topical corticosteroids rarely produces these effects but should be administered cautiously nonetheless in patients with a history of cataracts, glaucoma, or increased intraocular pressure, especially when potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) are used in the periorbital area. Topical corticosteroids may be systemically absorbed, depending on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios.
Hyperadrenocorticism
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Hyperadrenocorticism.
The use of topical corticosteroids may precipitate or aggravate conditions of hyperadrenocorticism. Systemic absorption of these agents can produce reversible hypothalamic-pituitary-adrenal axis suppression. Systemic absorption, depends on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios. Patients with an altered skin barrier or liver failure are also at increased risk. If possible, the use of highly potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) should be avoided in children and limited to small areas for 2 weeks in adults. The development of symptoms such as menstrual irregularities, acneiform lesions, cataracts and cushingoid features during topical corticosteroid therapy may indicate excessive use.
Hypokalemia
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Hypokalemia.
Hypokalemia may commonly occur during treatment with insulin. Use with caution in patients who may be particularly at risk of developing hypokalemia (e.g., patients using potassium-lowering medications, patients taking medications sensitive to serum potassium concentrations).
Infection
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Infection.
Topical corticosteroids may be systemically absorbed, depending on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Clinically significant local as well as systemic immunosuppressant and anti-inflammatory effects may occur, which can cause or exacerbate an infection. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios. Therapy with topical corticosteroids should be administered cautiously in patients with latent or active infections, particularly if a potent agent is used on a large area for prolonged periods or if occlusive dressings are used. Effective antimicrobial therapy or other appropriate treatment should be instituted to treat the infection. If possible, the use of highly potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) should be avoided in children and limited to small areas for 2 weeks in adults. Occlusive dressings should not be used in patients with skin infection.
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Infection.
Rapid acting inhaled insulin may predispose certain patients to develop diabetic ketoacidosis (DKA). In clinical trials, subjects with type 1 diabetes receiving inhaled insulin were more likely to develop DKA than patients receiving comparator agents. It is recommended to increase the frequency of glucose monitoring and to consider using an alternate route of administration, if appropriate, in patients at risk for DKA, such as patients with an acute illness or infections.
Liver Disease
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Liver Disease.
The use of topical corticosteroids may precipitate or aggravate conditions of hyperadrenocorticism. Systemic absorption of these agents can produce reversible hypothalamic-pituitary-adrenal axis suppression. Systemic absorption, depends on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios. Patients with an altered skin barrier or liver failure are also at increased risk. If possible, the use of highly potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) should be avoided in children and limited to small areas for 2 weeks in adults. The development of symptoms such as menstrual irregularities, acneiform lesions, cataracts and cushingoid features during topical corticosteroid therapy may indicate excessive use.
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Liver Disease.
Insulin requirements may be diminished in patients with renal or hepatic impairment due to reduced insulin metabolism and, in the latter case, also to reduced capacity for gluconeogenesis. Lower initial dosages may be appropriate, with careful monitoring of plasma glucose levels and dosing adjustments.
Lung Cancer
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Lung Cancer.
In clinical trials, lung cancer was observed in smoker and non-smoker patients using inhaled insulin. In patients with active lung cancer, a prior history of lung cancer, or in patients at risk for lung cancer, it is recommended to consider whether the benefits of inhaled insulin use outweigh this potential risk.
Malnourishment
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Malnourishment.
Hypoglycemia may commonly occur during treatment with insulin and/or oral hypoglycemic agents. Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during the use of these drugs, including those who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents.
Panhypopituitarism
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Panhypopituitarism.
Hypoglycemia may commonly occur during treatment with insulin and/or oral hypoglycemic agents. Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during the use of these drugs, including those who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents.
Renal Dysfunction
Moderate:
insulin inhalation, rapid acting
Insulin inhalation, rapid acting has a moderate potential interaction with Renal Dysfunction.
Insulin requirements may be diminished in patients with renal or hepatic impairment due to reduced insulin metabolism and, in the latter case, also to reduced capacity for gluconeogenesis. Lower initial dosages may be appropriate, with careful monitoring of plasma glucose levels and dosing adjustments.
Tuberculosis, Latent
Moderate:
Halog
The halcinonide topical in Halog has a moderate potential interaction with Tuberculosis, Latent.
Topical corticosteroids may be systemically absorbed, depending on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Clinically significant local as well as systemic immunosuppressant and anti-inflammatory effects may occur, which can cause or exacerbate an infection. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios. Therapy with topical corticosteroids should be administered cautiously in patients with latent or active infections, particularly if a potent agent is used on a large area for prolonged periods or if occlusive dressings are used. Effective antimicrobial therapy or other appropriate treatment should be instituted to treat the infection. If possible, the use of highly potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) should be avoided in children and limited to small areas for 2 weeks in adults. Occlusive dressings should not be used in patients with skin infection.
More resources
Halog
A total of 51 drugs are known to interact with Halog.
- Halog is in the drug class topical steroids.
- Halog is used to treat the following conditions:
insulin inhalation, rapid acting
A total of 476 drugs are known to interact with insulin inhalation, rapid acting.
- Insulin inhalation, rapid acting is in the drug class insulin.
- Insulin inhalation, rapid acting is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
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