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Drug interactions between Gleevec and Tylenol

Results for the following 2 drugs:
Gleevec (imatinib)
Tylenol (acetaminophen)

Interactions between your drugs

Moderate

acetaminophen imatinib

Applies to: Tylenol (acetaminophen) and Gleevec (imatinib)

Talk to your doctor before using imatinib together with acetaminophen. Imatinib may cause liver damage, and taking it with acetaminophen-containing products may increase that risk. You should also avoid or limit the use of alcohol while being treated with either of these medications. Call your doctor immediately if you experience fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

imatinib food

Applies to: Gleevec (imatinib)

Grapefruit juice may increase the blood levels and effects of certain medications such as imatinib. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with imatinib. However, if you have been regularly consuming grapefruit or grapefruit juice with imatinib, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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