Can you take Freeze It with Red yeast rice?
1 drug interaction and 2 additional warnings found for the following 2 drugs:
- Freeze It (camphor/menthol topical)
- red yeast rice
Drug interactions
Minor drug interactions
Minor:
menthol topical red yeast rice
Applies to: Freeze It (camphor / menthol topical) and red yeast rice
Information for this minor interaction is available on the professional version.
Food/lifestyle interactions
Major food/lifestyle interactions
Major:
red yeast rice Food/Lifestyle
Applies to: red yeast rice
Grapefruit juice can significantly increase the blood levels of red yeast rice. This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death. You should avoid the consumption of grapefruit or grapefruit juice during treatment with red yeast rice. Drinking green tea or taking green tea extracts may also increase the blood levels of red yeast rice in some patients. Talk to your doctor or pharmacist if you have any questions or concerns. It may be advisable to avoid excessive consumption of green tea and green tea products while on red yeast rice. Let your doctor know immediately if you have unexplained muscle pain, tenderness, or weakness during treatment, especially if these symptoms are accompanied by fever or dark colored urine. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Disease interactions
1 potential interaction Applies to: 1 condition, including Renal Dysfunction.
Renal Dysfunction
Moderate:
red yeast rice
Red yeast rice has a moderate potential interaction with Renal Dysfunction.
Some HMG-CoA reductase inhibitors (e.g., fluvastatin) have not been studied in patients with severe renal dysfunction or end-stage renal disease. Some others (e.g., pitavastatin, simvastatin) require a dose reduction when used in this group of patients. Caution and close monitoring are advised when using these drugs in patients with renal dysfunction.
More resources
Freeze It
A total of 364 drugs are known to interact with Freeze It.
- Freeze it is in the drug class topical rubefacient.
- Freeze it is used to treat the following conditions:
red yeast rice
A total of 311 drugs are known to interact with red yeast rice.
- Red yeast rice is in the following drug classes: nutraceutical products, statins.
- Red yeast rice is used to treat High Cholesterol.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.