Drug Interactions between fosphenytoin and lacosamide
This report displays the potential drug interactions for the following 2 drugs:
- fosphenytoin
- lacosamide
Interactions between your drugs
fosphenytoin lacosamide
Applies to: fosphenytoin and lacosamide
Coadministration with strong inducers of CYP450 enzymes may moderately decrease the plasma concentrations of lacosamide. It has been estimated that the systemic exposure of lacosamide decreased by 25% during concurrent use with enzyme-inducing antiepileptic agents. The clinical significance is unknown. Caution is advised whenever a CYP450 inducer is added to or withdrawn from therapy.
References (2)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- (2008) "Product Information. Vimpat (lacosamide)." UCB Pharma Inc
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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