Drug Interactions between ethinyl estradiol / norethindrone and Levall 5.0
This report displays the potential drug interactions for the following 2 drugs:
- ethinyl estradiol/norethindrone
- Levall 5.0 (guaifenesin/hydrocodone/phenylephrine)
Interactions between your drugs
No interactions were found between ethinyl estradiol / norethindrone and Levall 5.0. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
ethinyl estradiol / norethindrone
A total of 495 drugs are known to interact with ethinyl estradiol / norethindrone.
- Ethinyl estradiol / norethindrone is in the following drug classes: contraceptives, sex hormone combinations.
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Ethinyl estradiol / norethindrone is used to treat the following conditions:
- Abnormal Uterine Bleeding (off-label)
- Acne
- Birth Control
- Endometriosis (off-label)
- Gonadotropin Inhibition (off-label)
- Menstrual Disorders (off-label)
- Osteoporosis (off-label)
- Polycystic Ovary Syndrome (off-label)
- Postmenopausal Symptoms
- Prevention of Osteoporosis
Levall 5.0
A total of 730 drugs are known to interact with Levall 5.0.
- Levall 5.0 is in the drug class upper respiratory combinations.
- Levall 5.0 is used to treat Cough and Nasal Congestion.
Drug and food interactions
HYDROcodone food
Applies to: Levall 5.0 (guaifenesin / hydrocodone / phenylephrine)
Do not use alcohol or medications that contain alcohol while you are receiving treatment with HYDROcodone. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. If you are taking certain long-acting formulations of hydrocodone, consumption of alcohol may also cause rapid release of the drug, resulting in high blood levels that may be potentially lethal. Likewise, you should avoid consuming grapefruit and grapefruit juice, as this may increase the blood levels and effects of hydrocodone. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Do not use more than the recommended dose of HYDROcodone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
norethindrone food
Applies to: ethinyl estradiol / norethindrone
Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
ethinyl estradiol food
Applies to: ethinyl estradiol / norethindrone
Consumer information for this interaction is not currently available.
MONITOR: Coadministration of ethinyl estradiol may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 1A2. In a study of 30 healthy volunteers administered the CYP450 1A2 substrate tizanidine, the systemic exposure (AUC) of tizanidine was 3.9 times greater in women using an oral contraceptive containing ethinyl estradiol.
MANAGEMENT: Patients should be monitored for increased adverse effects of the CYP450 1A2 substrate during concomitant use with ethinyl estradiol. Product labeling for the specific CYP450 1A2 substrate should be consulted for additional recommendations.
phenylephrine food
Applies to: Levall 5.0 (guaifenesin / hydrocodone / phenylephrine)
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ethinyl estradiol food
Applies to: ethinyl estradiol / norethindrone
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: ethinyl estradiol / norethindrone
Information for this minor interaction is available on the professional version.
norethindrone food
Applies to: ethinyl estradiol / norethindrone
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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