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Drug Interactions between Entresto and Verquvo

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

valsartan vericiguat

Applies to: Entresto (sacubitril / valsartan) and Verquvo (vericiguat)

Using valsartan together with vericiguat may have additive effects. These medications work by dilating the blood vessels and combining them may cause symptomatic low blood pressure with symptoms of fainting, chest pain., dizziness, lightheadedness, fainting, flushing, and headache. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

valsartan food

Applies to: Entresto (sacubitril / valsartan)

If you are taking valsartan you should avoid potassium-containing salt substitutes or over-the-counter potassium supplements without first talking to your doctor. This can cause high levels of potassium in your blood. High levels of potassium can cause weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Call your doctor at once if you have any of these symptoms.

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Moderate

vericiguat food

Applies to: Verquvo (vericiguat)

Food significantly enhances the absorption of vericiguat. You should take each dose of vericiguat at the same time each day with food. If you receive enteral nutrition (tube feeding), take vericiguat with your feeding. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking vericiguat with food. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.