Drug Interactions between entacapone and tolcapone
This report displays the potential drug interactions for the following 2 drugs:
- entacapone
- tolcapone
Interactions between your drugs
No interactions were found between entacapone and tolcapone. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
entacapone
A total of 277 drugs are known to interact with entacapone.
- Entacapone is in the drug class dopaminergic antiparkinsonism agents.
- Entacapone is used to treat Parkinson's Disease.
tolcapone
A total of 289 drugs are known to interact with tolcapone.
- Tolcapone is in the drug class dopaminergic antiparkinsonism agents.
- Tolcapone is used to treat Parkinson's Disease.
Drug and food interactions
tolcapone food
Applies to: tolcapone
Alcohol can increase the nervous system side effects of tolcapone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with tolcapone. Do not use more than the recommended dose of tolcapone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
entacapone food
Applies to: entacapone
Alcohol can increase the nervous system side effects of entacapone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with entacapone. Do not use more than the recommended dose of entacapone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Comt inhibitors for parkinsonism
Therapeutic duplication
The recommended maximum number of medicines in the 'COMT inhibitors for parkinsonism' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'COMT inhibitors for parkinsonism' category:
- entacapone
- tolcapone
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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