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Drug Interactions between dengue vaccine and yellow fever vaccine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

yellow fever vaccine dengue vaccine

Applies to: yellow fever vaccine and dengue vaccine

ADJUST DOSING INTERVAL: The safety, immunogenicity, and efficacy of dengue vaccine when administered concurrently with other live viral or bacterial vaccines have not been adequately assessed. According to the U.S. Centers for Disease Control and Prevention's (CDC) Advisory Committee on Immunization Practices, no safety or immunogenicity issues have been reported in early trials evaluating coadministration of dengue vaccine with yellow fever vaccine or the measles, mumps, and rubella (MMR) vaccine. However, clinical data evaluating the concomitant or sequential administration of dengue vaccine with other live vaccines are not available.

MANAGEMENT: The CDC's Advisory Committee on Immunization Practices generally recommends that doses of injectable, live attenuated vaccines not administered simultaneously be separated by an interval of at least 28 days. Current local immunization guidelines and prescribing information for individual vaccines should be consulted for specific recommendations.

References

  1. "Product Information. DENGVAXIA (dengue vaccine)." sanofi pasteur (2022):
  2. CDC Centers for Disease Control and Prevention "Dengue Vaccine. Vaccine Schedule & Dosing. https://www.cdc.gov/dengue/vaccine/hcp/schedule-dosing.html" (2022):
  3. Adams L, Paz-Bailey G, Wong JM, et al. "Dengue Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021. MMWR Recomm Rep 2021 https://www.cdc.gov/mmwr/volumes/70/rr/rr7006a1.htm?s_cid=rr7006a1_w" (2022):

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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