yellow fever vaccine
Generic Name: yellow fever vaccine (YEL oh FEE ver)
Brand Name: YF-Vax
What is yellow fever vaccine?
Yellow fever is a serious disease caused by a virus that is spread through the bite of an infected mosquito. Yellow fever can cause fever and flu-like illness, jaundice (yellowing of the eyes and skin), liver failure, lung failure, kidney failure, vomiting of blood, and possibly death.
Yellow fever vaccine is recommended for people who plan to live in or travel to areas where yellow fever is known to exist, or those who are otherwise at high risk of coming into contact with the virus.
This vaccine is used to help prevent yellow fever in adults and children who are at least 9 months old. The vaccine works by exposing you to a small dose of the virus, which causes the body to develop immunity to the disease. Yellow fever vaccine will not treat an active infection that has already developed in the body.
You should receive the vaccine at least 10 days prior to your arrival in an area where you may be exposed to the virus.
This vaccine is also recommended for people who work in a research laboratory and may be exposed to yellow fever virus through needle-stick accidents or inhalation of viral droplets in the air.
Like any vaccine, the yellow fever vaccine may not provide protection from disease in every person.
What is the most important information I should know about yellow fever vaccine?
You should not receive a booster vaccine if you had a life threatening allergic reaction after the first shot.
What should I discuss with my healthcare provider before receiving yellow fever vaccine?
You should not receive this vaccine if you have ever had a life-threatening allergic reaction to a yellow fever vaccine, or if you have:
an allergy to gelatin, eggs, or egg product;
cancer, leukemia, or lymphoma;
weak immune system (caused by disease or by using certain medicine);
a disorder such as myasthenia gravis, DiGeorge syndrome, or tumor of the thymus gland;
if your thymus has been surgically removed; or
if you are breast-feeding a baby.
If you have a high risk of exposure to yellow fever, you may need to receive the vaccine even if you have an allergy to eggs or chicken products. Your doctor can give you the vaccine in several small doses to avoid an allergic reaction.
Children younger than 9 months old should not receive this vaccine, and should not travel to areas where yellow fever is known to exist.
You can still receive a vaccine if you have a cold or fever. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.
To make sure yellow fever vaccine is safe for you, tell your doctor if you have:
a history of seizures;
a neurologic disorder or disease affecting the brain (or if this was a reaction to a previous vaccine);
a history of Guillain Barré syndrome; or
an allergy to latex rubber.
It is not known whether yellow fever vaccine will harm an unborn baby. However, if you are at a high risk for infection with yellow fever during pregnancy, your doctor should determine whether you need this vaccine.
You should not receive this vaccine if you are breast-feeding a baby.
How is yellow fever vaccine given?
This vaccine is given as an injection (shot) into a muscle.
Yellow fever vaccine is given every 10 years to people who are at risk of exposure to yellow fever. The first shot can be given to a child who is at least 9 months old. Your individual booster schedule may be different from these guidelines. Follow your doctor's instructions or the schedule recommended by your local health department or the Centers for Disease Control and Prevention (CDC).
After receiving the vaccine, you will be given an International Certificate of Vaccination (yellow card) from the office or clinic where you receive your yellow fever vaccine. You will need this card as proof of vaccination to enter certain countries. This card becomes valid 10 days after you receive the vaccination and remains valid for 10 years.
In addition to receiving yellow fever vaccine, use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could infect you with the yellow fever virus.
This vaccine can cause false results on a skin test for tuberculosis for up to 6 weeks. Tell any doctor who treats you if you have received a yellow fever vaccine within the past 4 to 6 weeks.
If you continue to travel or live in areas where yellow fever is common, you should receive a booster dose of yellow fever vaccine every 10 years.
What happens if I miss a dose?
Talk with your doctor if you are receiving this vaccine less than 10 days prior to your arrival in an area where you may be exposed to the yellow fever virus.
Be sure you receive a booster dose of yellow fever vaccine every 10 years if you continue to travel or live in areas where yellow fever is common. If you do not receive the vaccine every 10 years, you may not be fully protected against the disease.
What happens if I overdose?
An overdose of this vaccine is unlikely to occur.
What should I avoid before or after receiving yellow fever vaccine?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Yellow fever vaccine side effects
Get emergency medical help if you have any of these signs of an allergic reaction: pale skin, hives; weakness, dizziness, difficulty breathing, rapid heart rate; swelling of your face, lips, tongue, or throat.
You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first vaccine. Keep track of any and all side effects you have after receiving this vaccine. If you ever need to receive a booster dose, you will need to tell your doctor if the previous shot caused any side effects.
Becoming infected with yellow fever is much more dangerous to your health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is extremely low.
Call your doctor at once if you have any of these rare but serious side effects (may occur up to 30 days after you receive the vaccine):
flu symptoms, stiff neck or back, vomiting, confusion, memory loss, irritability, loss of balance or coordination;
weakness or prickly feeling in your fingers or toes, sensitivity to light;
problems with walking, breathing, speech, swallowing, vision, or eye movement;
severe lower back pain, loss of bladder or bowel control;
muscle weakness or loss of movement in any part of your body; or
behavior changes, seizure (black-out or convulsions).
Common side effects (may occur for 5 to 10 days after you receive the vaccine) include:
low fever, mild headache, general ill feeling;
mild rash, muscle pain, weakness; or
pain, tenderness, swelling, or a lump where the shot was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.
See also: Side effects (in more detail)
Yellow fever vaccine dosing information
Usual Adult Dose for Yellow Fever Prophylaxis:
0.5 mL subcutaneously at least 10 days before travel. Booster doses are recommended every 10 years if there is continued risk of exposure.
Usual Pediatric Dose for Yellow Fever Prophylaxis:
>= 9 months: 0.5 mL subcutaneously at least 10 days before travel. Booster doses are recommended every 10 years if there is continued risk of exposure.
What other drugs will affect yellow fever vaccine?
Before receiving this vaccine, tell the doctor about all other vaccines you have recently received.
Also tell the doctor if you have recently received drugs or treatments that can weaken the immune system, including:
an oral, nasal, inhaled, or injectable steroid medicine;
medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders; or
medicines to treat or prevent organ transplant rejection.
This list is not complete and other drugs may interact with this vaccine. Tell your doctor about all medications you use. This includes prescription, over the counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More about yellow fever vaccine
- Other brands: YF-Vax
Related treatment guides
Where can I get more information?
- Your doctor or pharmacist can provide more information about this vaccine. Additional information is available from your local health department or the Centers for Disease Control and Prevention.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 4.01.
Date modified: January 10, 2017
Last reviewed: March 25, 2014