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Can you take Delgocitinib topical with Teplizumab?

1 drug interaction and 1 additional warning found for the following 2 drugs:

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Drug interactions

Moderate drug interactions

Moderate:

teplizumab delgocitinib topical

Applies to: teplizumab and delgocitinib topical

Using teplizumab together with delgocitinib topical can increase the risk of serious and potentially life-threatening infections, as well as some cancers. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. Contact your doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food/lifestyle interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease interactions

1 potential interaction Applies to: 1 condition, including Infection.

Infection

Moderate:

teplizumab

Teplizumab has a moderate potential interaction with Infection.

Use of teplizumab is not recommended in patients with active serious infection or chronic infection other than localized skin infections. Patients should be monitored for signs and symptoms of infection during and after treatment. If serious infection develops, discontinue treatment and treat appropriately.

More resources

delgocitinib topical

A total of 334 drugs are known to interact with delgocitinib topical.

teplizumab

A total of 177 drugs are known to interact with teplizumab.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.