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Darunavir Drug Interactions

Currently displaying 140 drugs known to have a major interaction with darunavir.

See also: The most common drugs checked in combination with this medicine.

Check for interactions with darunavir

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Medications known to interact with darunavir

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  • caffeine / ergotamine (Cafergot, Cafatine, Wigraine, Cafetrate, Ercaf, Migergot)
  • carbamazepine (Tegretol, Carbatrol, Epitol, Tegretol XR, Equetro, Carnexiv)
  • carbinoxamine / hydrocodone / phenylephrine (Excof, Donatussin MAX, Excof-SF, Max HC)
  • carbinoxamine / hydrocodone / pseudoephedrine (Histex HC, Tri-Vent HC, Mintex HC)
  • cerivastatin (Baycol)
  • chlorpheniramine / guaifenesin / hydrocodone / pseudoephedrine (Z-Tuss 2)
  • chlorpheniramine / hydrocodone (Tussionex Pennkinetic, Hydrocodone GF, TussiCaps, Vituz, S-T Forte 2, HyTan, Novasus)
  • chlorpheniramine / hydrocodone / phenylephrine (Hydrocodone CP, Cyndal HD, Coughtuss, Quindal HD, Hydron CP, Endagen-HD, Chemdal HD, Iodal HD, Rindal-HD, Ed-TLC, Efasin-HD, Guiaphen HD, Mintuss MS, Vanex-HD, Chemdal HD Plus, Nasatuss, Iotussin HC, Chlorgest HD, Ed-Tuss HC, Hyphen-HD, Tuss-PD, KG-Dal HD, Endotuss-HD, Ditussin-HC, Chemtussin HC, Exo-Tuss, Endal-HD Plus, Enplus-HD, Comtussin HC, Tuss-HC, Ventuss Syrup, Maxi-Tuss SA, Maxi-Tuss HC, Histinex HC, KG-Dal HD Plus, Highland HC, Uni Tuss HC, H-C Tussive, Histussin HC Liquid, Cytuss HC, Tuss-DS, Efasin-HD Plus, Quindal HD Plus, Hi-Tuss HC, Chlorphen HD, Duradal HD, Liquitussin HC Syrup, Hydrocodone HD, Tussive HC, B-Tuss, Hydro-PC II, De-Chlor HD, De-Chlor HC, Atuss MS, Hydro-PC II Plus, Triant-HC, Uni-Tricof HC, Rindal HD Plus, Echotuss-HC, Phendal-HD, Relacon-HC NR, Tusana-D, Neo HC, Poly-Tussin HD, Liquicough HC, Relasin-HC, DroTuss-CP, Z-Cof HC, Maxi-Tuss HCX, Relacon-HC)
  • chlorpheniramine / hydrocodone / pseudoephedrine (Zutripro, Hydron PCS, Notuss-Forte, Notuss, Detuss, Histinex PV, JayCof-HC, Pediatex HC, Tussend, Welltuss HC, Hexatussin, Hyphed, Tussin-V, Q-V Tussin, A-G Tussin, KG-Tussin, P-V-Tussin Syrup, Hydrotuss HC, Hydrocof-HC, Cordron-HC, Cordron-HC NR, Atuss HD, Atuss HS)
  • cilostazol (Pletal)
  • cisapride (Propulsid)
  • cobimetinib (Cotellic)
  • colchicine (Colcrys, Mitigare)
  • colchicine / probenecid (Probenecid and Colchicine, Proben-C)
  • cyclosporine (Neoral, Gengraf, Sandimmune)
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  • glecaprevir / pibrentasvir (Mavyret)
  • guaifenesin / hydrocodone (Execlear, Narcof, Condasin, Vicotuss, Kwelcof, Fentuss Expectorant, Vortex, Pneumotussin 2.5, Monte-G HC, Flowtuss, Obredon, CodiCLEAR DH, Maxi-Tuss HCG, EndaCof-Tab, Ztuss ZT, Tusso-HC, Vicodin Tuss, Hycotuss Expectorant, Pneumotussin HC, Propatuss Expectorant, Vi-Q-Tuss, Co-Tussin, Codotuss, Co-Tuss V Expectorant, Vicoclear, Endacof XP, Hycosin Expectorant, G-Tuss, Hycoclar Tuss, Cotuss V, Vitussin Expectorant, Hydrotuss, Gua HC, Hycoclear, Hydrocod-GF, Medcodin, Entuss, Pneumotussin, Tusso-DF, Execof, Pancof XP, Touro HC, Xpect-HC, Atuss HX, Extendryl HC, Hydro-Tussin HG, Canges-XP, Z-Cof HCX, Tussicle, A-Cof DH, Relasin-HCX)
  • guaifenesin / hydrocodone / pheniramine / phenylephrine / phenylpropanolamine (S-T Forte)
  • guaifenesin / hydrocodone / pheniramine / phenylpropanolamine / pyrilamine
  • guaifenesin / hydrocodone / phenylephrine (Tussafed-HCG, Mintuss G, Atuss G, Ambi 5/15/100, Tussafed-HC, Levall 5.0, Hydro GP, De-Chlor G, Dynatuss HC, Uni-Lev 5.0, Crantex HC, Duratuss HD, Simuc-HD, Gentex HC, Donatussin DC, Guiaplex HC, Exetuss-HC, Qual-Tussin DC, Nariz HC, MonteFlu HC, Nazarin HC, HydroFed)
  • guaifenesin / hydrocodone / pseudoephedrine (Hycofenix, Entuss-D JR, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, SRC Expectorant, Nalex Expectorant, Deconamine CX, Poly-Tussin XP, Entuss-D, Hydrotussin HD, KG-Tuss HD, Medtuss HD, Spantuss HD, Vanacon, Su-Tuss HD Elixir, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Hydro-Tuss XP, Dynex HD, Entex HC, Pseudatex HC)
  • guanfacine (Intuniv, Tenex)
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darunavir alcohol/food Interactions

There is 1 alcohol/food interaction with darunavir

darunavir disease Interactions

There are 3 disease interactions with darunavir which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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