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Drug Interactions between dapsone topical and Dvorah

This report displays the potential drug interactions for the following 2 drugs:

  • dapsone topical
  • Dvorah (acetaminophen/caffeine/dihydrocodeine)

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Interactions between your drugs

Moderate

acetaminophen dapsone topical

Applies to: Dvorah (acetaminophen / caffeine / dihydrocodeine) and dapsone topical

Talk to your doctor before using acetaminophen together with dapsone topical. Acetaminophen can cause a condition called methemoglobinemia that reduces the oxygen-carrying capacity of the blood to different organs, and combining the medication with dapsone topical may increase the risk. Infants and patients with certain conditions such as glucose-6-phosphate dehydrogenase deficiency or anemia are more likely to develop this condition. You should seek immediate medical attention if you notice signs and symptoms such as a gray discoloration of the skin, mouth, or nail bed; nausea; headache; dizziness; lightheadedness; fatigue; shortness of breath; rapid or shallow breathing; a rapid heartbeat; anxiety; and confusion. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Minor

caffeine food

Applies to: Dvorah (acetaminophen / caffeine / dihydrocodeine)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.