Can you take Copper with Goserelin?
No drug interactions found, but 8 warnings to review for the following 2 drugs:
- Copper (copper gluconate)
- goserelin
Drug interactions
There were no interactions found between Copper and goserelin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
8 potential interactions Applies to: 8 conditions, including Heart Failure, Osteoporosis, Diabetes Mellitus, Liver Disease, and Long QT Syndrome.
Biliary Obstruction
Moderate:
Copper
The copper gluconate in Copper has a moderate potential interaction with Biliary Obstruction.
The trace elements, copper and manganese, are excreted in the bile. Copper and manganese doses may need to be adjusted, reduced, or omitted in patients with liver disease or biliary obstruction.
Cardiovascular Conditions and Disorders
Moderate:
goserelin
Goserelin has a moderate potential interaction with Cardiovascular Conditions and Disorders.
Increased risk of developing myocardial infarction, sudden cardiac death and stroke has been reported in association with use of GnRH agonists such as goserelin in men. The risk appears low based on the reported odds ratios, and should be evaluated carefully along with cardiovascular risk factors when determining a treatment for patients with prostate cancer.
Diabetes Mellitus
Moderate:
goserelin
Goserelin has a moderate potential interaction with Diabetes Mellitus.
Hyperglycemia and an increased risk of developing diabetes have been reported in men receiving GnRH agonists such as goserelin. Hyperglycemia may represent development of diabetes mellitus or worsening of glycemic control in patients with diabetes. Monitor blood glucose and/or glycosylated hemoglobin (HbA1c) periodically in patients receiving goserelin and manage with current practice for treatment of hyperglycemia or diabetes.
Heart Failure
Moderate:
goserelin
Goserelin has a moderate potential interaction with Heart Failure.
Androgen deprivation therapy may prolong the QT/QTc interval. Health care providers should consider whether the benefits of androgen deprivation therapy outweigh the potential risks in patients with congenital long QT syndrome, congestive heart failure, frequent electrolyte abnormalities, and in patients taking drugs known to prolong the QT interval. Electrolyte abnormalities should be corrected. Consider periodic monitoring of electrocardiograms and electrolytes.
Liver Disease
Moderate:
Copper
The copper gluconate in Copper has a moderate potential interaction with Liver Disease.
The trace elements, copper and manganese, are excreted in the bile. Copper and manganese doses may need to be adjusted, reduced, or omitted in patients with liver disease or biliary obstruction.
Long QT Syndrome
Moderate:
goserelin
Goserelin has a moderate potential interaction with Long QT Syndrome.
Androgen deprivation therapy may prolong the QT/QTc interval. Health care providers should consider whether the benefits of androgen deprivation therapy outweigh the potential risks in patients with congenital long QT syndrome, congestive heart failure, frequent electrolyte abnormalities, and in patients taking drugs known to prolong the QT interval. Electrolyte abnormalities should be corrected. Consider periodic monitoring of electrocardiograms and electrolytes.
Malabsorption Syndrome
Moderate:
Copper
The copper gluconate in Copper has a moderate potential interaction with Malabsorption Syndrome.
The trace metals manganese, chromium, copper, selenium, and zinc are absorbed in the GI tract from dietary sources and following administration of oral supplements. GI absorption may be decreased in patients with malabsorption syndromes. Therefore, larger dosages may be required when these supplements are given orally. Parenteral administration may be appropriate.
Osteoporosis
Moderate:
goserelin
Goserelin has a moderate potential interaction with Osteoporosis.
The use of GnRH agonists in women may cause a reduction in bone mineral density. In women, current available data suggest that recovery of bone loss occurs on cessation of therapy in the majority of patients. Postmarketing data has also shown osteoporosis, decreased bone mineral density and bone fracture in men. Therapy with goserelin should be administered cautiously in patients with major risk factors for decreased bone mineral content, such as chronic alcohol and/or tobacco use, a strong family history of osteoporosis, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, corticosteroids).
More resources
Copper
A total of 28 drugs are known to interact with Copper.
- Copper is in the drug class minerals and electrolytes.
- Copper is used to treat Vitamin/Mineral Supplementation and Deficiency.
goserelin
A total of 300 drugs are known to interact with goserelin.
- Goserelin is in the following drug classes: gonadotropin releasing hormones, hormones/antineoplastics.
- Goserelin is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.