Drug Interactions between Carlson D and magnesium hydroxide / mineral oil
This report displays the potential drug interactions for the following 2 drugs:
- Carlson D (cholecalciferol)
- magnesium hydroxide/mineral oil
Interactions between your drugs
magnesium hydroxide cholecalciferol
Applies to: magnesium hydroxide / mineral oil and Carlson D (cholecalciferol)
GENERALLY AVOID: Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to potentially additive pharmacologic effects. Chronic hypermagnesemia may have a role in the pathogenesis of adynamic bone disease in dialysis patients.
MANAGEMENT: Patients on chronic renal dialysis treated with a vitamin D analog should avoid magnesium-containing products.
References
- "Product Information. Rocaltrol (calcitriol)." Roche Laboratories PROD (2001):
- "Product Information. Zemplar (paricalcitol)." Abbott Pharmaceutical PROD (2001):
- "Product Information. Hectorol (doxercalciferol)." Genzyme Corporation (2004):
- "Product Information. One-Alpha (alfacalcidol)." Pharmel Inc (2004):
mineral oil cholecalciferol
Applies to: magnesium hydroxide / mineral oil and Carlson D (cholecalciferol)
ADJUST DOSING INTERVAL: Coadministration of mineral oil and oral vitamin D (a fat soluble vitamin) may lead to decreased effectiveness of vitamin D. Mineral oil most likely decreases gastrointestinal absorption of vitamin D.
MANAGEMENT: Consider either separating the doses by at least 3 hours, substituting mineral oil with alternative therapy or using parenteral vitamin D.
References
- "Product Information. Hectorol (doxercalciferol)." Genzyme Corporation PROD (2001):
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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