Drug Interactions between Cabometyx and tivozanib
This report displays the potential drug interactions for the following 2 drugs:
- Cabometyx (cabozantinib)
- tivozanib
Interactions between your drugs
No interactions were found between Cabometyx and tivozanib. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Cabometyx
A total of 531 drugs are known to interact with Cabometyx.
- Cabometyx is in the following drug classes: multikinase inhibitors, VEGF/VEGFR inhibitors.
- Cabometyx is used to treat the following conditions:
tivozanib
A total of 62 drugs are known to interact with tivozanib.
- Tivozanib is in the drug class VEGF/VEGFR inhibitors.
- Tivozanib is used to treat Renal Cell Carcinoma.
Drug and food interactions
cabozantinib food
Applies to: Cabometyx (cabozantinib)
Cabozantinib should be taken on an empty stomach, one hour before or two hours after a meal. Do not consume grapefruit, grapefruit juice, or any supplements that contain grapefruit extract during treatment with cabozantinib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of cabozantinib. You may be more likely to experience side effects such as nausea; vomiting; diarrhea; loss of appetite; weight loss; mouth sores; abdominal pain; skin rash (primarily on the palms of the hands and soles of the feet); delayed wound healing; high blood pressure; and impaired bone marrow function resulting in low numbers of different types of blood cells, which can increase the risk of bleeding problems and infections. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Vegf/vegfr inhibitors
Therapeutic duplication
The recommended maximum number of medicines in the 'VEGF/VEGFR inhibitors' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'VEGF/VEGFR inhibitors' category:
- Cabometyx (cabozantinib)
- tivozanib
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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