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Drug Interactions between bupivacaine liposome and Polydine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Minor

povidone iodine topical BUPivacaine liposome

Applies to: Polydine (povidone iodine topical) and bupivacaine liposome

Topical antiseptics such as povidone iodine have a surface-active nature and may interact with lipids from bupivacaine liposomal formulation. The clinical significance is unknown. Contact between bupivacaine liposomal and antiseptics such as povidone iodine in solution should be avoided. Interactions are not expected if the site where the topical antiseptic solution is applied is allowed to dry completely before administering bupivacaine liposomal injection.

References

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.