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Drug Interactions between brimonidine / brinzolamide ophthalmic and topiramate

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

brimonidine ophthalmic topiramate

Applies to: brimonidine / brinzolamide ophthalmic and topiramate

After using brimonidine ophthalmic, some of the medication may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Combining it with topiramate or other medications that can also have these effects may increase the risk. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

topiramate brinzolamide ophthalmic

Applies to: topiramate and brimonidine / brinzolamide ophthalmic

Talk to your doctor before using brinzolamide ophthalmic together with topiramate. After brinzolamide ophthalmic is instilled into the eye, the medication can be absorbed into the bloodstream and cause some of the same effects as topiramate. This may increase the risk and/or severity of side effects like drowsiness, dizziness, numbness, tingling, ringing in the ears, loss of appetite, nausea, vomiting, diarrhea, kidney stones, fever, and heat stroke. You should drink plenty of fluids while being treated with topiramate, especially during exercise or prolonged exposure to warm temperatures. Let your doctor know if you experience sudden back pain, abdominal pain, blood in the urine, painful urination, numbness or tingling in the hands and feet, decreased sweating, or a rise in body temperature. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer