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Drug Interactions between Biktarvy and Dovato

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

lamiVUDine emtricitabine

Applies to: Dovato (dolutegravir / lamivudine) and Biktarvy (bictegravir / emtricitabine / tenofovir alafenamide)

Using lamiVUDine together with emtricitabine is generally not recommended. Combining these medications is not expected to substantially enhance activity against HIV. In fact, there is reason to believe that overall effectiveness may diminish due to possible antagonistic effects pertaining to how these medications are activated in the body. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Minor

tenofovir food

Applies to: Biktarvy (bictegravir / emtricitabine / tenofovir alafenamide)

Information for this minor interaction is available on the professional version.

Minor

dolutegravir food

Applies to: Dovato (dolutegravir / lamivudine)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Integrase strand transfer inhibitors

Therapeutic duplication

The recommended maximum number of medicines in the 'integrase strand transfer inhibitors' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'integrase strand transfer inhibitors' category:

  • Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide)
  • Dovato (dolutegravir/lamivudine)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer