Drug Interactions between Benadryl and Talwin Nx
This report displays the potential drug interactions for the following 2 drugs:
- Benadryl (diphenhydramine)
- Talwin Nx (naloxone/pentazocine)
Interactions between your drugs
Applies to: Benadryl (diphenhydramine) and Talwin Nx (naloxone / pentazocine)
Using diphenhydrAMINE together with pentazocine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Applies to: Talwin Nx (naloxone / pentazocine) and Talwin Nx (naloxone / pentazocine)
The following interaction applies only if you are using naloxone in an injectable formulation:
naloxone can reverse the effects of pentazocine. If you are a physically dependent patient you may experience withdrawal symptoms. This can cause nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: Talwin Nx (naloxone / pentazocine)
Smoking tobacco may reduce the blood levels and effects of pentazocine. Contact your doctor if pentazocine is not adequately controlling your symptoms.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.