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Drug Interactions between atovaquone / proguanil and typhoid vaccine, live

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

typhoid vaccine, live proguanil

Applies to: typhoid vaccine, live and atovaquone / proguanil

Ask your doctor before using typhoid vaccine, live together with proguanil. In some situations, proguanil can decrease the effectiveness of typhoid vaccine, live. Medications containing single agent proguanil should not be administered until at least 10 days after the last dose of typhoid vaccine, live. However, the fixed combination atovaquone-proguanil at doses used for malaria prevention can be given concurrently with typhoid vaccine, live. This vaccine works by exposing you to a small dose of the virus or a protein from the virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

atovaquone food

Applies to: atovaquone / proguanil

Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone at the same time each day with a meal or a milky drink. If you receive enteral nutrition (tube feeding), take atovaquone with your feeding. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking atovaquone with food.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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