Drug Interactions between atezolizumab and cobimetinib
This report displays the potential drug interactions for the following 2 drugs:
Interactions between your drugs
No interactions were found between atezolizumab and cobimetinib. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
- Atezolizumab is in the drug class anti-PD-1 monoclonal antibodies.
- Atezolizumab is used to treat the following conditions:
- Cobimetinib is in the drug class multikinase inhibitors.
- Cobimetinib is used to treat Melanoma, Metastatic.
Drug and food interactions
Applies to: cobimetinib
Grapefruit juice may increase the blood levels and effects of certain medications such as cobimetinib. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with cobimetinib. However, if you have been regularly consuming grapefruit or grapefruit juice with cobimetinib, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.