Drug Interactions between Antinaus 50 and isotretinoin
This report displays the potential drug interactions for the following 2 drugs:
- Antinaus 50 (promethazine)
- isotretinoin
Interactions between your drugs
No interactions were found between Antinaus 50 and isotretinoin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Antinaus 50
A total of 689 drugs are known to interact with Antinaus 50.
- Antinaus 50 is in the following drug classes: antihistamines, phenothiazine antiemetics.
- Antinaus 50 is used to treat the following conditions:
isotretinoin
A total of 141 drugs are known to interact with isotretinoin.
- Isotretinoin is in the following drug classes: miscellaneous antineoplastics, miscellaneous uncategorized agents.
-
Isotretinoin is used to treat the following conditions:
- Acne
- Acute Nonlymphocytic Leukemia (off-label)
- Granuloma Annulare (off-label)
- Melanoma, Metastatic (off-label)
- Pityriasis rubra pilaris (off-label)
- Rosacea (off-label)
Drug and food interactions
promethazine food
Applies to: Antinaus 50 (promethazine)
GENERALLY AVOID: Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment. Also, ethanol may precipitate dystonic reactions in patients who are taking phenothiazines. The two drugs probably act on different sites in the brain, although the exact mechanism of the interaction is not known.
MANAGEMENT: Patients should be advised to avoid alcohol during phenothiazine therapy.
References (2)
- Lutz EG (1976) "Neuroleptic-induced akathisia and dystonia triggered by alcohol." JAMA, 236, p. 2422-3
- Freed E (1981) "Alcohol-triggered-neuroleptic-induced tremor, rigidity and dystonia." Med J Aust, 2, p. 44-5
ISOtretinoin food
Applies to: isotretinoin
GENERALLY AVOID: The combined use of ethanol and isotretinoin may result in a disulfiram-like reaction. The mechanism has not been established.
MANAGEMENT: Alcohol consumption should be avoided during isotretinoin therapy.
References (1)
- (2001) "Product Information. Accutane (isotretinoin)." Roche Laboratories
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.