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Can you take Aloe vera with Saxagliptin?

1 drug interaction and 3 additional warnings found for the following 2 drugs:

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Drug interactions

Moderate drug interactions

Moderate:

aloe vera sAXagliptin

Applies to: aloe vera and saxagliptin

Talk to your doctor before using aloe vera if you are diabetic. Depending on the dose and formulation, regular use of aloe vera may lower blood glucose levels in some patients, which may lead to a reduction in your dosage requirement of sAXagliptin or any other diabetic medications you are receiving.

Your blood glucose should be closely monitored so that medications may be adjusted accordingly by your doctor.

Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include:

  • headache
  • dizziness
  • drowsiness
  • nervousness
  • confusion
  • tremor
  • nausea
  • hunger
  • weakness
  • perspiration
  • palpitation
  • rapid heartbeat

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food/lifestyle interactions

Moderate food/lifestyle interactions

Moderate:

sAXagliptin Food/Lifestyle

Applies to: saxagliptin

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink.

You should avoid using alcohol if your diabetes is not well controlled or if you have:

  • high triglycerides
  • neuropathy (nerve damage)
  • pancreatitis

Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan.

Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia.

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Disease interactions

2 potential interactions Applies to: 2 conditions, including Pancreatitis and Renal Dysfunction.

Pancreatitis

Moderate:

saxagliptin

sAXagliptin has a moderate potential interaction with Pancreatitis.

There have been postmarketing reports of acute pancreatitis in patients taking DPP-4 inhibitors. These drugs should be used with caution in patients with a history of pancreatitis or pancreatic disease, although it is unknown if they are at increased risk. Patients should be observed for signs and symptoms of pancreatitis during treatment. If pancreatitis is suspected, treatment should be discontinued immediately and appropriate management should be initiated.

Renal Dysfunction

Moderate:

saxagliptin

sAXagliptin has a moderate potential interaction with Renal Dysfunction.

It is recommended to assess renal function prior to initiating treatment with DPP-4 inhibitors and periodically thereafter. Patients with moderate to severe renal insufficiency and end stage renal dysfunction will require a dose adjustment. Linagliptin will not require a dose adjustment per manufacturer's information. Additionally, there have been postmarketing reports of worsening renal function in some patients with renal insufficiency taking sitagliptin at inappropriate doses.

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More resources

aloe vera

A total of 50 drugs are known to interact with aloe vera.

saxagliptin

A total of 473 drugs are known to interact with saxagliptin.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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