Drug Interactions between allopurinol and Prenatal Rx
This report displays the potential drug interactions for the following 2 drugs:
- allopurinol
- Prenatal Rx (multivitamin, prenatal)
Interactions between your drugs
No interactions were found between allopurinol and Prenatal Rx. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
allopurinol
A total of 431 drugs are known to interact with allopurinol.
- Allopurinol is in the following drug classes: antigout agents, antihyperuricemic agents.
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Allopurinol is used to treat the following conditions:
- Calcium Oxalate Calculi with Hyperuricosuria
- Cardiothoracic Surgery (off-label)
- Gout
- High Risk Percutaneous Transluminal Angioplasty (off-label)
- Hyperuricemia Secondary to Chemotherapy
- Leishmaniasis (off-label)
- Mania (off-label)
- Reactive Perforating Collangenosis (off-label)
- Urinary Tract Stones (off-label)
Prenatal Rx
A total of 161 drugs are known to interact with Prenatal Rx.
- Prenatal rx is in the following drug classes: iron products, vitamin and mineral combinations.
- Prenatal rx is used to treat Vitamin/Mineral Supplementation during Pregnancy/Lactation.
Drug and food interactions
allopurinol food
Applies to: allopurinol
ADJUST DOSING INTERVAL: The tolerability of allopurinol may be improved by giving it after a meal. Additionally, when the dose is greater than 300 mg, dividing the total daily dose into smaller doses administered more often may be appropriate to help minimize gastrointestinal irritation.
MONITOR: Concomitant use of allopurinol with central nervous system (CNS) depressants, including alcohol, may potentiate adverse effects such as somnolence and sedation.
MANAGEMENT: To improve tolerability, some manufacturers suggest administering allopurinol after a meal. Additionally, if the daily dose is greater than 300 mg, administering allopurinol in divided doses may help reduce gastrointestinal intolerance. Patients should also be counseled to avoid or limit consumption of alcohol and to avoid activities requiring mental alertness such as driving or operating hazardous machinery until they know how the medication affects them.
References
- (2024) "Product Information. Allopurinol (Sandoz) (allopurinol)." Sandoz Pty Ltd
- (2021) "Product Information. Zyloric (allopurinol)." Aspen Pharma Trading Ltd
- (2021) "Product Information. Zyloprim (allopurinol)." AA Pharma Inc, 248178
- (2024) "Product Information. Allopurinol (allopurinol)." Actavis U.S. (Purepac Pharmaceutical Company)
multivitamin, prenatal food
Applies to: Prenatal Rx (multivitamin, prenatal)
ADJUST DOSING INTERVAL: Concomitant use of some oral medications may reduce the bioavailability of orally administered iron, and vice versa.
Food taken in conjunction with oral iron supplements may reduce the bioavailability of the iron. However, in many patients intolerable gastrointestinal side effects occur necessitating administration with food.
MANAGEMENT: Ideally, iron products should be taken on an empty stomach (i.e., at least 1 hour before or 2 hours after meals), but if this is not possible, administer with meals and monitor the patient more closely for a subtherapeutic effect. Some studies suggest administration of iron with ascorbic acid may enhance bioavailability. In addition, administration of oral iron products and some oral medications should be separated whenever the bioavailability of either agent may be decreased. Consult the product labeling for specific separation times and monitor clinical responses as appropriate.
References
- "Product Information. Feosol (ferrous sulfate)." SmithKline Beecham
- (2021) "Product Information. Accrufer (ferric maltol)." Shield Therapeutics
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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