Drug Interactions between Adoxa TT and allopurinol

Allopurinol should generally be taken after a meal to reduce side effects. If your daily dose exceeds 300 mg, you may also ask your healthcare provider if it is okay to divide the total daily dose into smaller doses given more frequently instead of once a day, as this may also reduce stomach upset that can happen with allopurinol. It is best to avoid or limit the consumption of alcohol, as it can increase drowsiness or other nervous system side effects of allopurinol. You should also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Iron can bind to doxycycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and doxycycline should preferably be taken at least three to four hours apart in most cases. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.