Drug Interactions between adapalene / benzoyl peroxide topical and Lyrica
This report displays the potential drug interactions for the following 2 drugs:
- adapalene/benzoyl peroxide topical
- Lyrica (pregabalin)
Interactions between your drugs
benzoyl peroxide topical adapalene topical
Applies to: adapalene / benzoyl peroxide topical and adapalene / benzoyl peroxide topical
GENERALLY AVOID: Concomitant use of retinoids and keratolytic or astringent topicals may result in excessive irritation and/or drying.
MANAGEMENT: Depending on circumstances (e.g., areas of application), concomitant use should preferably be avoided, and a rest period considered in between use of these products.
References
- "Product Information. Retin-A (tretinoin)." Ortho McNeil Pharmaceutical PROD (2001):
- "Product Information. Tazorac (tazarotene topical)." Allergan Inc PROD (2001):
Drug and food interactions
pregabalin food
Applies to: Lyrica (pregabalin)
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
References
- Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7
- Gilman AG, eds., Nies AS, Rall TW, Taylor P "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: Pergamon Press Inc. (1990):
- "Product Information. Fycompa (perampanel)." Eisai Inc (2012):
- "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc (2015):
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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