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Drug Interactions between Accutane and tretinoin topical

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

tretinoin topical ISOtretinoin

Applies to: tretinoin topical and Accutane (isotretinoin)

Using ISOtretinoin together with tretinoin topical may increase skin irritation. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

ISOtretinoin food

Applies to: Accutane (isotretinoin)

Ask your doctor before using ISOtretinoin together with ethanol (alcohol). Do not drink alcohol while you are taking ISOtretinoin. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Check your food and medicine labels to be sure these products do not contain alcohol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Retinoic acid derivatives

Therapeutic duplication

The recommended maximum number of medicines in the 'retinoic acid derivatives' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'retinoic acid derivatives' category:

  • Accutane (isotretinoin)
  • tretinoin topical

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.