Skip to main content

Can you take Acarbose with Somatropin?

1 drug interaction and 31 additional warnings found for the following 2 drugs:

Add/remove drugs

Drug interactions

Moderate drug interactions

Moderate:

somatropin acarbose

Applies to: somatropin and acarbose

Somatropin may interfere with blood glucose control and reduce the effectiveness of acarbose and other diabetic medications.

Monitor your blood sugar levels closely. You may need a dose adjustment of your diabetic medications during and after treatment with somatropin.

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food/lifestyle interactions

Moderate food/lifestyle interactions

Moderate:

acarbose Food/Lifestyle

Applies to: acarbose

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink.

You should avoid using alcohol if your diabetes is not well controlled or if you have:

  • high triglycerides
  • neuropathy (nerve damage)
  • pancreatitis

Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan.

Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia.

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate:

somatropin Alcohol (Ethanol)

Applies to: somatropin

Talk to your healthcare provider before using somatropin together with caffeine as somatropin may alter the blood levels and effects of caffeine. The importance of this interaction may be higher in certain patients, depending on what caffeine is being used to treat.

You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your healthcare provider if your symptoms worsen or your condition changes during treatment with these medications.

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate:

somatropin Alcohol (Ethanol)

Applies to: somatropin

Talk to your healthcare provider before using somatropin together with ethanol (alcohol) as somatropin may alter the blood levels and effects of ethanol (alcohol). The importance of this interaction may be higher in certain patients, depending on what ethanol (alcohol) is being used to treat.

You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your healthcare provider if your symptoms worsen or your condition changes during treatment with these medications.

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate:

somatropin Caffeine

Applies to: somatropin

Talk to your healthcare provider before using somatropin together with caffeine as somatropin may alter the blood levels and effects of caffeine. The importance of this interaction may be higher in certain patients, depending on what caffeine is being used to treat.

You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your healthcare provider if your symptoms worsen or your condition changes during treatment with these medications.

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate:

somatropin Caffeine

Applies to: somatropin

Talk to your healthcare provider before using somatropin together with ethanol (alcohol) as somatropin may alter the blood levels and effects of ethanol (alcohol). The importance of this interaction may be higher in certain patients, depending on what ethanol (alcohol) is being used to treat.

You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your healthcare provider if your symptoms worsen or your condition changes during treatment with these medications.

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Disease interactions

26 potential interactions Applies to: 25 conditions, including Weight Loss, Underactive Thyroid, Breast Cancer, Sleep Apnea, and Prostate Cancer.

Acute Abdomen

Major:

somatropin

Somatropin has a major potential interaction with Acute Abdomen.

Treatment with somatropin and somatrogon is contraindicated in patients with acute critical illness due to any complications following open heart surgery, abdominal surgery, multiple trauma, or acute respiratory failure. Patients with these conditions have an increased risk of mortality.

Bladder Cancer

Major:

somatropin

Somatropin has a major potential interaction with Bladder Cancer.

Somatropin and somatrogon are contraindicated in the presence of any active malignancy. Any preexistent malignancy should be inactive and its treatment should be completed prior to somatropin therapy. This includes the presence of any intracranial tumor. Somatropin and somatrogon should be discontinued if there is any evidence of recurrence.

Brain Tumor

Major:

somatropin

Somatropin has a major potential interaction with Brain Tumor.

Somatropin and somatrogon are contraindicated in the presence of any active malignancy. Any preexistent malignancy should be inactive and its treatment should be completed prior to somatropin therapy. This includes the presence of any intracranial tumor. Somatropin and somatrogon should be discontinued if there is any evidence of recurrence.

Breast Cancer

Major:

somatropin

Somatropin has a major potential interaction with Breast Cancer.

Somatropin and somatrogon are contraindicated in the presence of any active malignancy. Any preexistent malignancy should be inactive and its treatment should be completed prior to somatropin therapy. This includes the presence of any intracranial tumor. Somatropin and somatrogon should be discontinued if there is any evidence of recurrence.

Cirrhosis

Major:

acarbose

Acarbose has a major potential interaction with Cirrhosis.

The use of acarbose is contraindicated in patients with primary cirrhosis.

Colonic Ulceration

Major:

acarbose

Acarbose has a major potential interaction with Colonic Ulceration.

The use of alpha-glucosidase inhibitors is contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, or any chronic intestinal disease associated with marked disorders of digestion or absorption. Alpha-glucosidase inhibitors competitively inhibit enzymes involved in the digestion of carbohydrates. Increased gas formation in the intestines due to fermentation of the undigested carbohydrates can worsen or aggravate intestinal problems.

Diabetes Mellitus

Moderate:

somatropin

Somatropin has a moderate potential interaction with Diabetes Mellitus.

The use of growth hormone has been associated with resistance to insulin. Patients with diabetes mellitus or impaired glucose tolerance should be observed closely during therapy. The dose of antihyperglycemic drugs (insulin or oral/injectable agents) may require adjustment.

Diabetic Ketoacidosis

Major:

acarbose

Acarbose has a major potential interaction with Diabetic Ketoacidosis.

The use of alpha-glucosidase inhibitors is contraindicated for the treatment of patients with diabetic ketoacidosis.

Diabetic Retinopathy

Major:

somatropin

Somatropin has a major potential interaction with Diabetic Retinopathy.

Somatropin, somatrogon , and lonapegsomatropin are contraindicated in patients with active proliferative or severe non-proliferative diabetic retinopathy since treatment may worsen condition.

Intestinal Obstruction

Major:

acarbose

Acarbose has a major potential interaction with Intestinal Obstruction.

The use of alpha-glucosidase inhibitors is contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, or any chronic intestinal disease associated with marked disorders of digestion or absorption. Alpha-glucosidase inhibitors competitively inhibit enzymes involved in the digestion of carbohydrates. Increased gas formation in the intestines due to fermentation of the undigested carbohydrates can worsen or aggravate intestinal problems.

Liver Disease

Moderate:

acarbose

Acarbose has a moderate potential interaction with Liver Disease.

The use of acarbose has been associated with dose-related elevations in serum transaminase levels and, rarely, hyperbilirubinemia and jaundice. Hepatic adverse effects may be more likely to occur at dosages exceeding 50 mg three times a day. Therapy with acarbose should be administered cautiously in patients with liver disease. Monitoring of serum transaminases is recommended every 3 months during the first year of treatment and periodically thereafter. If hepatotoxicity is suspected at any time, a dosage reduction or withdrawal of therapy may be indicated.

Lung Cancer

Major:

somatropin

Somatropin has a major potential interaction with Lung Cancer.

Somatropin and somatrogon are contraindicated in the presence of any active malignancy. Any preexistent malignancy should be inactive and its treatment should be completed prior to somatropin therapy. This includes the presence of any intracranial tumor. Somatropin and somatrogon should be discontinued if there is any evidence of recurrence.

Malabsorption Syndrome

Major:

acarbose

Acarbose has a major potential interaction with Malabsorption Syndrome.

The use of alpha-glucosidase inhibitors is contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, or any chronic intestinal disease associated with marked disorders of digestion or absorption. Alpha-glucosidase inhibitors competitively inhibit enzymes involved in the digestion of carbohydrates. Increased gas formation in the intestines due to fermentation of the undigested carbohydrates can worsen or aggravate intestinal problems.

Noninfectious Colitis

Major:

acarbose

Acarbose has a major potential interaction with Noninfectious Colitis.

The use of alpha-glucosidase inhibitors is contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, or any chronic intestinal disease associated with marked disorders of digestion or absorption. Alpha-glucosidase inhibitors competitively inhibit enzymes involved in the digestion of carbohydrates. Increased gas formation in the intestines due to fermentation of the undigested carbohydrates can worsen or aggravate intestinal problems.

Papilledema Associated with Increased Intracranial Pressure

Moderate:

somatropin

Somatropin has a moderate potential interaction with Papilledema Associated with Increased Intracranial Pressure.

Intracranial hypertension with papilledema, visual changes, nausea and/or vomiting has been reported in a small number of patients treated with somatropin, somatrogon , and lonapegsomatropin . Fundoscopic examination should be performed before treatment initiation to exclude preexisting papilledema, and should be continued periodically during treatment. If papilledema is observed during treatment, therapy should be stopped. Treatment could be restarted at a lower dose once intracranial hypertension has been resolved. Patients with Turner Syndrome might be at increased risk of developing intracranial hypertension.

Prostate Cancer

Major:

somatropin

Somatropin has a major potential interaction with Prostate Cancer.

Somatropin and somatrogon are contraindicated in the presence of any active malignancy. Any preexistent malignancy should be inactive and its treatment should be completed prior to somatropin therapy. This includes the presence of any intracranial tumor. Somatropin and somatrogon should be discontinued if there is any evidence of recurrence.

Pulmonary Impairment

Major:

somatropin

Somatropin has a major potential interaction with Pulmonary Impairment.

Somatropin and somatrogon is contraindicated in patients with Prader-Willi Syndrome who are severely obese, have a history of upper airway obstruction or sleep apnea, or have severe respiratory impairment. There have been reports of sudden death when somatropin was used in such patients.

Major:

somatropin

Somatropin has a major potential interaction with Pulmonary Impairment.

Treatment with somatropin and somatrogon is contraindicated in patients with acute critical illness due to any complications following open heart surgery, abdominal surgery, multiple trauma, or acute respiratory failure. Patients with these conditions have an increased risk of mortality.

Renal Dysfunction

Major:

acarbose

Acarbose has a major potential interaction with Renal Dysfunction.

Acarbose may accumulate in patients with renal impairment. Following oral administration, 35% of a dose is recovered in the urine as either the parent drug or metabolites. However, long-term clinical trials in diabetic patients with significant renal dysfunction (serum creatinine > 2.0 mg/dL) have not been conducted. Therapy with acarbose should be administered cautiously in patients with renal dysfunction. The manufacturer does not recommend its use in patients with significantly impaired renal function.

Scoliosis

Moderate:

somatropin

Somatropin has a moderate potential interaction with Scoliosis.

Progression of scoliosis can occur in patients who experience rapid growth. Since somatropin and somatrogon increase growth rate, children with a history of scoliosis should be monitored for progression of this condition. Physicians should be alert for this skeletal abnormality which can be commonly seen in patients with Turner and Prader-Willi syndromes, and can manifest during somatropin and somatrogon treatment.

Sepsis

Major:

somatropin

Somatropin has a major potential interaction with Sepsis.

Treatment with somatropin and somatrogon is contraindicated in patients with acute critical illness due to any complications following open heart surgery, abdominal surgery, multiple trauma, or acute respiratory failure. Patients with these conditions have an increased risk of mortality.

Skin Cancer

Major:

somatropin

Somatropin has a major potential interaction with Skin Cancer.

Somatropin and somatrogon are contraindicated in the presence of any active malignancy. Any preexistent malignancy should be inactive and its treatment should be completed prior to somatropin therapy. This includes the presence of any intracranial tumor. Somatropin and somatrogon should be discontinued if there is any evidence of recurrence.

Sleep Apnea

Major:

somatropin

Somatropin has a major potential interaction with Sleep Apnea.

Somatropin and somatrogon is contraindicated in patients with Prader-Willi Syndrome who are severely obese, have a history of upper airway obstruction or sleep apnea, or have severe respiratory impairment. There have been reports of sudden death when somatropin was used in such patients.

Turner Syndrome

Moderate:

somatropin

Somatropin has a moderate potential interaction with Turner Syndrome.

Somatropin may increase the risk of otitis media in patients with Turner syndrome. These patients should be evaluated carefully for otitis media and other ear disorders as they have an increased risk of ear and hearing disorders.

Underactive Thyroid

Moderate:

somatropin

Somatropin has a moderate potential interaction with Underactive Thyroid.

The use of growth hormone has been associated with the development of hypothyroidism. Patients should be monitored baseline and periodically for adequate thyroid function. Inadequate treatment of hypothyroidism may inhibit the optimal response to growth hormone.

Weight Loss

Major:

somatropin

Somatropin has a major potential interaction with Weight Loss.

Somatropin and somatrogon is contraindicated in patients with Prader-Willi Syndrome who are severely obese, have a history of upper airway obstruction or sleep apnea, or have severe respiratory impairment. There have been reports of sudden death when somatropin was used in such patients.

More resources

acarbose

A total of 336 drugs are known to interact with acarbose.

somatropin

A total of 654 drugs are known to interact with somatropin.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.