Gonadotropin-releasing hormone antagonists
What are Gonadotropin-releasing hormone antagonists?
*Gonadotropin-releasing hormone (GnRH) antagonists are synthetic analogs of gonadotropin-releasing hormone, which is produced by the hypothalamus and controls the secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary. Gonadotropin-releasing hormone antagonists bind to gonadotropin-releasing hormone receptors and decrease the effect of gonadotropin-releasing hormone.
In men, gonadotropin-releasing hormone antagonists inhibit the release of luteinizing hormone, and consequently less testosterone is produced. Testosterone stimulates the growth of many forms of prostate cancer. Gonadotropin-releasing hormone antagonists are used to treat prostate cancer as by reducing the levels of testosterone the size of prostate cancer is reduced.
Gonadotropin-releasing hormone antagonists are used to treat women undergoing fertility treatment. It prevents early release of luteinizing hormone (LH) and premature ovulation in women being administered follicle-stimulating hormone (FSH) when preparing for in-vitro fertilization.
List of Gonadotropin-releasing hormone antagonists
| Drug Name | Avg. Rating | Reviews |
|---|---|---|
| degarelix systemic (Pro) Brand name: Firmagon |
15 reviews | |
| relugolix systemic (Pro) Brand name: Orgovyx |
24 reviews | |
| elagolix systemic (Pro) Brand name: Orilissa |
131 reviews | |
| ganirelix systemic (Pro) Brand name: Fyremadel | No reviews | |
| cetrorelix systemic (Pro) Brand name: Cetrotide | No reviews | |
| For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). | ||
See also
Medical conditions treated or associated with gonadotropin-releasing hormone antagonists:
Further information
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