Rabies Vaccine, Purified Chick Embryo Cell Dosage
Medically reviewed by Drugs.com. Last updated on Nov 23, 2020.
Applies to the following strengths: 2.5 intl units
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Rabies Prophylaxis
Preexposure prophylaxis: 1 mL intramuscularly on days 0, 7, and 21 or 28
-Preexposure prophylaxis does not eliminate the need for additional therapy after a known rabies exposure.
Postexposure vaccination:
-Previously unvaccinated: 1 mL intramuscularly on days 0, 3, 7, 14, and 28
-Previously vaccinated against rabies: 1 mL intramuscularly on days 0 and 3
Comments:
-Immunizations series are usually started and completed with 1 vaccine product
-No studies are available on the efficacy or frequency of adverse events when switching products during treatment, however this product elicited protective antibody titers when used as a booster dose for persons who received a primary series with Human Diploid Cell Vaccine.
Usual Pediatric Dose for Rabies Prophylaxis
Preexposure prophylaxis: 1 mL intramuscularly on days 0, 7, and 21 or 28
-Preexposure prophylaxis does not eliminate the need for additional therapy after a known rabies exposure.
Postexposure vaccination:
-Previously unvaccinated: 1 mL intramuscularly on days 0, 3, 7, 14, and 28
-Previously vaccinated against rabies: 1 mL intramuscularly on days 0 and 3
Comments:
-Immunizations series are usually started and completed with 1 vaccine product
-No studies are available on the efficacy or frequency of adverse events when switching products during treatment, however this product elicited protective antibody titers when used as a booster dose for persons who received a primary series with Human Diploid Cell Vaccine.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
Preexposure prophylaxis: Anaphylactic reaction to any of the ingredients
Postexposure prophylaxis: None. In view of and almost invariable fatal outcome of rabies, no contraindications exist, including pregnancy
To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS) at: https://vaers.hhs.gov
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
-For intramuscular administration only.
-The deltoid is the preferred administration site for adults, and the anterolateral aspect of the thigh for infants and small children.
-Avoid the gluteal region as lower neutralizing antibodies may result.
-Unintentional intravascular administration may cause systemic reactions including shock.
-Use immediately after reconstitution.
Storage requirements: Refrigerate, protect from light
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