Rabies Vaccine, Purified Chick Embryo Cell Dosage

Medically reviewed by Drugs.com. Last updated on Jan 6, 2025.

Usual Adult Dose for Rabies Prophylaxis

Preexposure prophylaxis: 1 mL intramuscularly on days 0, 7, and 21 or 28

• Preexposure prophylaxis does not eliminate the need for additional therapy after a known rabies exposure.

Postexposure vaccination:

• Previously unvaccinated: 1 mL intramuscularly on days 0, 3, 7, 14, and 28
• Previously vaccinated against rabies: 1 mL intramuscularly on days 0 and 3

Comments:

• Immunizations series are usually started and completed with 1 vaccine product
• No studies are available on the efficacy or frequency of adverse events when switching products during treatment, however this product elicited protective antibody titers when used as a booster dose for persons who received a primary series with Human Diploid Cell Vaccine.

Usual Pediatric Dose for Rabies Prophylaxis

Preexposure prophylaxis: 1 mL intramuscularly on days 0, 7, and 21 or 28

• Preexposure prophylaxis does not eliminate the need for additional therapy after a known rabies exposure.

Postexposure vaccination:

• Previously unvaccinated: 1 mL intramuscularly on days 0, 3, 7, 14, and 28
• Previously vaccinated against rabies: 1 mL intramuscularly on days 0 and 3

Comments:

• Immunizations series are usually started and completed with 1 vaccine product
• No studies are available on the efficacy or frequency of adverse events when switching products during treatment, however this product elicited protective antibody titers when used as a booster dose for persons who received a primary series with Human Diploid Cell Vaccine.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
Preexposure prophylaxis: Anaphylactic reaction to any of the ingredients
Postexposure prophylaxis: None. In view of and almost invariable fatal outcome of rabies, no contraindications exist, including pregnancy

To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS) at: https://vaers.hhs.gov

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For intramuscular administration only.
• The deltoid is the preferred administration site for adults, and the anterolateral aspect of the thigh for infants and small children.
• Avoid the gluteal region as lower neutralizing antibodies may result.
• Unintentional intravascular administration may cause systemic reactions including shock.
• Use immediately after reconstitution.

Storage requirements: Refrigerate, protect from light

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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