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Normosol-R Injection Dosage

Generic name: SODIUM CHLORIDE 526mg in 100mL, SODIUM ACETATE ANHYDROUS 222mg in 100mL, SODIUM GLUCONATE 502mg in 100mL, POTASSIUM CHLORIDE 37mg in 100mL, MAGNESIUM CHLORIDE 30mg in 100mL
Dosage form: injection, solution

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Medically reviewed by Last updated on Nov 6, 2020.

Normosol-R is administered by intravenous infusion. It may also be administered subcutaneously. The amount to be infused is based on replacement of losses of extracellular fluid volume in the individual patient. Up to 3 times the volume of estimated blood loss during and after surgery can be given to correct circulatory volume when there is only a moderate loss of blood.

Drug Interactions

Additives may be incompatible. Consult with pharmacist, if available. When introducing additives, use aseptic technique, mix thoroughly and do not store.

Parenteral drug products should be inspected visually for particulate matter or discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

Normosol-R does not contain calcium to avoid precipitation of calcium salts that may occur when certain drugs are added. Solutions which contain calcium in amounts exceeding the normal plasma concentration may enhance clotting on contact with citrated blood. Hence, Normosol-R can be used for starting blood transfusion.


To Open

Tear outer wrap at notch and remove solution container. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually. If supplemental medication is desired, follow directions below before preparing for administration.

To Add Medication

  1. Prepare additive port.

  2. Using aseptic technique and an additive delivery needle of appropriate length, puncture resealable additive port at target area, inner diaphragm and inject. Withdraw needle after injecting medication.

  3. The additive port may be protected by covering with an additive cap.

  4. Mix container contents thoroughly.

To Administer

  1. Attach administration set per manufacturer’s instructions.

  2. Regulate rate of administration per institutional policy.


Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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