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Normosol-R Side Effects

Generic name: lvp solution

Medically reviewed by Drugs.com. Last updated on Feb 22, 2025.

Note: This document provides detailed information about Normosol-R Side Effects associated with lvp solution. Some dosage forms listed on this page may not apply specifically to the brand name Normosol-R.

Applies to lvp solution: intraperitoneal solution.

Other dosage forms:

Important warnings This medicine can cause some serious health issues

Intraperitoneal route (solution)

False elevation of glucose levels has occurred, including up to 2 weeks following discontinuation of therapy, because icodextrin peritoneal dialysis solution interferes with glucose dehydrogenase pyrroloquinolinequinone (GDH-PQQ), glucose-dye-oxidoreductase (GDO), and some glucose dehydrogenase flavin-adenine dinucleotide (GDH-FAD)-based glucose measurements due to the presence of maltose.

Use only glucose-specific monitors and test strips in patients using icodextrin peritoneal dialysis solution.

Your doctor will check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly. Blood tests may be needed to check for unwanted effects.

If you measure your blood sugar levels, this solution may cause false high blood sugar readings for some kinds of monitors and test strips. You must use only a glucose-specific monitor and test strips. Ask your doctor or nurse to help you choose the right monitor and test strips. Your caregiver may suggest you carry a wallet card explaining your need for a specific kind of monitor and test strips.

Icodextrin may cause an infection in the peritoneal cavity called peritonitis. This is common in patients on peritoneal dialysis. Tell your doctor if you have pain, redness, fever, or cloudy drained fluid.

Icodextrin may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have blistering, peeling, or red skin rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

It is important for you to keep track of how much fluid you have in your body at all times. Ask your health caregiver about how to do this, and what to do if you have too much or too little fluid. One way to keep track of how much fluid is in your body is to weigh yourself often, and write the number down.

Tell your doctor about all other medicines you are using. Icodextrin might remove some medicines from your body, so your doctor might need to change your dose of other medicines. Do not change the dose of any of your other medicines unless your doctor tells you to.

Serious side effects of Normosol-R

Along with its needed effects, lvp solution (the active ingredient contained in Normosol-R) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lvp solution:

More common side effects

  • abdominal or stomach pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • blurred vision
  • body aches or pain
  • chills
  • confusion
  • convulsions
  • cough
  • decreased urine
  • difficulty with breathing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • ear congestion
  • fever
  • headache
  • increased thirst
  • irregular heartbeat
  • loss of appetite
  • loss of voice
  • muscle pain or cramps
  • nausea or vomiting
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • pale skin
  • pounding in the ears
  • rapid weight gain
  • runny or stuffy nose
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • sweating
  • tingling of the hands or feet
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight gain or loss

Less common side effects

  • chest pain
  • dry mouth
  • flushed, dry skin
  • fruit-like breath odor
  • increased hunger
  • increased urination
  • unexplained weight loss

Incidence not known

  • blistering, peeling, or loosening of the skin
  • diarrhea
  • difficulty with swallowing
  • hives, itching, or skin rash
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • redness or swelling at the catheter site
  • redness, soreness, or itching skin
  • sores, ulcers, or white spots in the mouth or on the lips
  • sores, welting, or blisters
  • tightness in the chest

Other side effects of Normosol-R

Some side effects of lvp solution may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • back pain
  • lack or loss of strength

Less common side effects

  • acid or sour stomach
  • belching
  • heartburn
  • indigestion
  • stomach discomfort, upset, or pain

See also:

Further information

Normosol-R side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer