Multitrace-4 Pediatric Dosage
Generic name: ZINC SULFATE HEPTAHYDRATE 4.39mg in 1mL, CUPRIC SULFATE 0.4mg in 1mL, MANGANESE SULFATE 77ug in 1mL, CHROMIC CHLORIDE 5.12ug in 1mL
Dosage form: injection, solution, concentrate
- Multitrace-4 injection, solution
- Multitrace-4 Concentrate injection, solution, concentrate
- Multitrace-4 Neonatal injection, solution
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Each mL of the solution provides Zinc 1 mg, Copper 0.1 mg, Manganese 25 mcg, and Chromium 1 mcg, and is administered intravenously only after dilution to a minimum of 1:200. The suggested dosage ranges for the four trace elements are:
ZINC: For full term infants and children, 100 mcg zinc/kg/day is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg zinc/kg/day is suggested.
COPPER: For pediatric patients, the suggested additive dosage level is 20 mcg copper/kg/day. The normal plasma range for copper is approximately 80 to 160 mcg/100 mL.
MANGANESE: For pediatric patients, a dosage level of 2 to 10 mcg manganese/kg/day is recommended.
CHROMIUM: For pediatric patients, the suggested additive dosage level is 0.14 to 0.20 mcg/kg/day.
Periodic monitoring of plasma levels of Zinc, Copper, Manganese, and Chromium is suggested as a guideline for administration.
Aseptic addition of the solution to the TPN solution under a laminar flow hood is recommended. The trace elements present in the solution are physically compatible with the electrolytes and vitamins usually present in the amino acid/dextrose solution used for TPN.
Parenteral drug products should be inspected visually for particulate matter and discoloration, whenever solution and container permit.
Store at 20°-25°C (68°-77°F); excursions permitted to 15°-30°C (59°-86°F) (See USP Controlled Room Temperature).