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Mecasermin Dosage

Medically reviewed by Last updated on May 15, 2023.

Applies to the following strengths: 10 mg/mL

Usual Pediatric Dose for Primary IGF-1 Deficiency

Initial dose: 0.4 to 0.8 mg/kg subcutaneously 2 times a day for at least 7 days

Maximum dose: 0.12 mg/kg subcutaneously 2 times a day


Uses: Treatment of growth failure in children with severe primary IGF-1 deficiency or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments



Safety and efficacy have not been established in patients younger than 2 years or older than 64 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

Storage requirements:

Reconstitution/preparation techniques:


Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.